Drug delivery to the lungs by inhalation offers a targeted drug therapy for respiratory
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …

Over the recent couple of decades, pharmaceutical field has embarked most phenomenal
noteworthy achievements in the field of medications as well as drug delivery. The rise of …

Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …

Biofilm-dispersing enzymes degrade the extracellular polymeric matrix surrounding bacterial
biofilms, disperse the microbial community and increase their susceptibility to antibiotics and …

Background: Pulmonary drug delivery is attractive for both local and systemic drug delivery
as a non-invasive route that provides a large surface area, thin epithelial barrier, high blood …

The objective of the present study was to evaluate the potential of paclitaxel loaded micelles
fabricated from PEG5000–DSPE as a sustained release system following pulmonary …

Abstract The Biopharmaceutics Classification System (BCS), developed in the 1990s for oral
immediate release drugs, is utilized by R&D scientists and regulators to streamline product …

Levofloxacin (LV) is a hydrophilic broad-spectrum antibiotic commonly used in pulmonary
treatment against recurrent infections of Pseudomonas aeruginosa, and particularly in cystic …

Introduction: Solid lipid particles were introduced in the early 1990s as an alternative drug
carrier system to emulsions, liposomes and polymeric microparticles. Although lipid …

The aim of this research was to investigate a potential standardized test method to
characterize the dissolution properties of formulations intended for pulmonary delivery. A …