Wnt signaling in the nervous system and in Alzheimer's disease

NC Inestrosa, L Varela-Nallar - Journal of molecular cell biology, 2014 - academic.oup.com
Wnts comprise a large family of proteins that have shown to be part of a signaling cascade
that regulates several aspects of development including organogenesis, midbrain …

WNT signaling in neuronal maturation and synaptogenesis

SB Rosso, NC Inestrosa - Frontiers in cellular neuroscience, 2013 - frontiersin.org
The Wnt signaling pathway plays a role in the development of the central nervous system
and growing evidence indicates that Wnts also regulates the structure and function of the …

Wnt signaling during synaptic development and plasticity

V Budnik, PC Salinas - Current opinion in neurobiology, 2011 - Elsevier
The formation of synaptic connections requires a dialogue between pre and postsynaptic
cells to coordinate the assembly of the presynaptic release machinery and the postsynaptic …

Wnt/β-catenin-dependent transcription in autism spectrum disorders

MO Caracci, ME Avila… - Frontiers in molecular …, 2021 - frontiersin.org
Autism spectrum disorders (ASD) is a heterogeneous group of neurodevelopmental
disorders characterized by synaptic dysfunction and defects in dendritic spine morphology …

Wnt signaling in the regulation of adult hippocampal neurogenesis

L Varela-Nallar, NC Inestrosa - Frontiers in cellular neuroscience, 2013 - frontiersin.org
In the adult brain new neurons are continuously generated mainly in two regions, the
subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) in the …

Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses

L Varela-Nallar, IE Alfaro, FG Serrano… - Proceedings of the …, 2010 - National Acad Sciences
Growing evidence indicates that Wingless-type (Wnt) signaling plays an important role in the
maturation of the central nervous system. We report here that Wingless-type family member …

Wnts in adult brain: from synaptic plasticity to cognitive deficiencies

CA Oliva, JY Vargas, NC Inestrosa - Frontiers in cellular …, 2013 - frontiersin.org
During development of the central nervous system the Wnt signaling pathway has been
implicated in a wide spectrum of physiological processes, including neuronal connectivity …

Crosstalk between MLO Y4 osteocytes and C2C12 muscle cells is mediated by the Wnt/β catenin pathway

J Huang, S Romero Suarez, N Lara… - Journal of Bone and …, 2017 - academic.oup.com
We examined the effects of osteocyte secreted factors on myogenesis and muscle function.
MLO Y4 osteocyte like cell conditioned media (CM)(10%) increased ex vivo soleus muscle …

Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients

H Fan, X Sun, W Guo, A Zhong, W Niu, L Zhao… - Journal of psychiatric …, 2014 - Elsevier
Currently, diagnosis and treatment of major depressive disorder (MDD) are based on the
patients' description of symptoms, mental status examinations, and clinical behavioral …

Wnt signaling in the central nervous system: new insights in health and disease

CA Oliva, C Montecinos-Oliva, NC Inestrosa - Progress in molecular …, 2018 - Elsevier
Since its discovery, Wnt signaling has been shown to be one of the most crucial
morphogens in development and during the maturation of central nervous system. Its action …