In our previous work, we designed and implemented a synthetic metabolic pathway for 1, 2, 3-trichloropropane (TCP) biodegradation in Escherichia coli. Significant effects of metabolic …
We present a novel tool for parameter synthesis of piecewise multi-affine dynamical systems from specifications expressed in a hybrid branching-time temporal logic. The tool is based …
We study the problem of determining the robustness of a multi-agent system of unbounded size against specifications expressed in a temporalepistemic logic. We introduce a …
JP Comet, H Collavizza, L Gibart - Theoretical Computer Science, 2024 - Elsevier
When modelling a complex biological system, the bottleneck of the process is the determination of parameter values that lead to model dynamics that are compatible with …
Complex behaviour arising in biological systems is described by highly parameterised dynamical models. Most of the parameters are mutually dependent and therefore it is hard …
Parametrised models of dynamical systems arise in various areas of science. In this work, we focus on models described as parametrised Kripke structures with properties formulated …
Formal verification techniques together with other computer science formal methods have been recently tailored for applications to biological and biomedical systems. In contrast to …
Mechanistic models in biology often involve numerous parameters about which we do not have direct experimental information. The traditional approach is to fit these parameters …
It has been our privilege to serve as the program chairs for CAV 2017, the 29th International Conference on Computer-Aided Verification. CAV 2017 was held in beautiful Heidelberg …