Contemporary review of testicular torsion: new concepts, emerging technologies and potential therapeutics

DG DaJusta, CF Granberg, C Villanueva… - Journal of pediatric …, 2013 - Elsevier
Testicular torsion is one of the few emergencies in pediatric urology which requires an
accurate and timely diagnosis in order to avoid testis loss. It is not an uncommon event …

Berberine inhibits the ischemia-reperfusion induced testicular injury through decreasing oxidative stress

IO Kazaz, A Mentese, S Demir, G Kerimoglu… - The American journal of …, 2020 - Elsevier
Purpose The aim of this study was to investigate the effect of berberine (BBR) on oxidative
stress in an experimental testicular I/R injury model. Methods Eighteen rats were divided into …

Protective effect of cerium oxide on testicular function and oxidative stress after torsion/detorsion in adult male rats

S Yesil, C Ozdemir, M Arslan… - Experimental and …, 2022 - spandidos-publications.com
Testicular torsion (T)/detorsion (D) can cause testicular injury due to the rotation of the
spermatic cord and its vessels, therefore it represents an urological emergency that is …

Beneficial effects of memantine on ischemia/reperfusion injury following torsion/detorsion induced testicular damage in rats: improvement in histological and …

A Jafari, H Ghasemnejad-Berenji, M Nemati… - Journal of Pediatric …, 2021 - Elsevier
Introduction Testicular torsion is a common urologic emergency and one of the causes of
infertility in males. Hence, prompt diagnosis and treatment are important to prevent testicular …

Alpha‐lipoic acid and N‐acetylcysteine protects intensive swimming exercise‐mediated germ‐cell depletion, pro‐oxidant generation, and alteration of …

K Jana, A Dutta, P Chakraborty, I Manna… - Molecular …, 2014 - Wiley Online Library
Prolonged and strenuous exercise has been proposed as a possible source of male‐factor
infertility. Forced intensive swimming has also been identified as one source of a …

[HTML][HTML] Protective effects of rutin and naringin in testicular ischemia-reperfusion induced oxidative stress in rats

BR Akondi, SR Challa, A Akula - Journal of reproduction & infertility, 2011 - ncbi.nlm.nih.gov
Methods 42 animals were selected for the study and divided into 7 groups, each containing
6 rats. Bioflavonoids were tested for their efficacy in reversing the damage done to the …

N‐acetyl cysteine attenuates diazinon exposure‐induced oxidative stress in rat testis

T Oksay, M Nazıroğlu, O Ergün, S Doğan, O Özatik… - Andrologia, 2013 - Wiley Online Library
The aim of this study was to investigate the gonadotoxic effects of diazinon and its
mechanism of action with special reference to its possible reactive oxygen species …

[HTML][HTML] A comparison of the effects of N-acetylcysteine and ethyl pyruvate on experimental testicular ischemia-reperfusion injury

S Turkmen, A Mentese, E Karaguzel, Y Karaca… - Fertility and sterility, 2012 - Elsevier
OBJECTIVE: To compare the effects of N-acetylcysteine (NAC) and ethyl pyruvate (EP) on
experimental testicular ischemia-reperfusion (I/R) injury. DESIGN: Randomized, controlled …

Inhibition of NOS-NO system prevents autoimmune orchitis development in rats: relevance of NO released by testicular macrophages in germ cell apoptosis and …

S Jarazo Dietrich, MI Fass, PV Jacobo, CMA Sobarzo… - PLoS …, 2015 - journals.plos.org
Background Although the testis is considered an immunoprivileged organ it can orchestrate
immune responses against pathological insults such as infection and trauma. Experimental …

N-acetylcysteine protects testicular tissue against ischemia/reperfusion injury via inhibiting endoplasmic reticulum stress and apoptosis

IO Kazaz, S Demir, E Yulug, F Colak, A Bodur… - Journal of Pediatric …, 2019 - Elsevier
Background In animal models, endoplasmic reticulum (ER) stress has been reported to play
a vital role in mediating ischemia/reperfusion (I/R) injury in certain organs, such as brain …