Intestinal fatty acid binding protein: A rising therapeutic target in lipid metabolism

X Huang, Y Zhou, Y Sun, Q Wang - Progress in Lipid Research, 2022 - Elsevier
Fatty acid binding proteins (FABPs) are key proteins in lipid transport, and the isoforms are
segregated according to their tissue origins. Several isoforms, such as adipose-FABP and …

Fatty Acid-Binding Proteins in Psoriasis—A Review

J Nowowiejska, A Baran, I Flisiak - Metabolites, 2022 - mdpi.com
Psoriasis is one of the most common skin diseases in dermatological practice. It affects
about 1–3% of the general population and is associated with different comorbidities …

Investigating protein‐membrane interactions using native reverse micelles constructed from naturally sourced lipids

SH Walters, AJ Castillo, AM Develin… - Protein …, 2023 - Wiley Online Library
Advancing the study of membrane associated proteins and their interactions is dependent
on accurate membrane models. While a variety of membrane models for high‐resolution …

Theory and computation of nuclear shielding

T Kupka - 2020 - books.rsc.org
A review of the literature published from January to December 2019 on theoretical aspects
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …

Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes

JM Gullett, MG Cuypers, CR Grace, S Pant… - Journal of Biological …, 2022 - ASBMB
Fatty acid (FA) transfer proteins extract FA from membranes and sequester them to facilitate
their movement through the cytosol. Detailed structural information is available for these …

Effects of ligand binding on dynamics of fatty acid binding protein and interactions with membranes

Y Lu, GZ Yang, D Yang - Biophysical Journal, 2022 - cell.com
Intracellular transport of fatty acids involves binding of ligands to their carrier fatty acid
binding proteins (FABPs) and interactions of ligand-free and-bound FABPs with membranes …

Conformational exchange of fatty acid binding protein induced by protein-nanodisc interactions

Y Lu, D Yang - Biophysical Journal, 2021 - cell.com
Fatty acid binding proteins (FABPs) can facilitate the transfer of long-chain fatty acids
between intracellular membranes across considerable distances. The transfer process …

Kruppel-like factor 5 enhances proliferation, lipid droplet formation and oxaliplatin resistance in colorectal cancer by promoting fatty acid binding protein 6 transcription

Q Zuo, Q Xu, Z Li, D Luo, H Peng, Z Duan - Anti-Cancer Drugs, 2023 - journals.lww.com
Oxaliplatin (OXA) is a standard agent for colorectal cancer (CRC) adjuvant chemotherapy.
However, acquired and intrinsic OXA resistance is a primary challenge for CRC treatment …

Lipid exchange in crystal‐confined fatty acid binding proteins: X‐ray evidence and molecular dynamics explanation

HA Alvarez, A Cousido‐Siah… - Proteins: Structure …, 2023 - Wiley Online Library
Fatty acid binding proteins (FABPs) are responsible for the long‐chain fatty acids (FAs)
transport inside the cell. However, despite the years, since their structure is known and the …

Brain fatty acid binding protein exhibits non-preferential and mutation-resistant binding towards fatty acids

I Bodnariuc, S Lenz, M Renaud-Young, TM Shandro… - BioRxiv, 2021 - biorxiv.org
Members of the fatty acid binding protein (FABP) family function as intracellular transporters
of long chain fatty acids and other hydrophobic molecules to different cellular compartments …