Past, present and future: 30 years of HIV research
F Barré-Sinoussi, AL Ross, JF Delfraissy - Nature Reviews Microbiology, 2013 - nature.com
This year marks the thirtieth anniversary of the publication of the study that first reported the
isolation of HIV-1. In this Timeline article, we provide a historical perspective of some of the …
isolation of HIV-1. In this Timeline article, we provide a historical perspective of some of the …
Microbial translocation in the pathogenesis of HIV infection and AIDS
G Marchetti, C Tincati, G Silvestri - Clinical microbiology reviews, 2013 - Am Soc Microbiol
In pathogenic simian immunodeficiency virus (SIV) and human immunodeficiency virus
(HIV) infections, the translocation of microbial products from the gastrointestinal (GI) tract to …
(HIV) infections, the translocation of microbial products from the gastrointestinal (GI) tract to …
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
JM Brenchley, DA Price, TW Schacker, TE Asher… - Nature medicine, 2006 - nature.com
Chronic activation of the immune system is a hallmark of progressive HIV infection and
better predicts disease outcome than plasma viral load, yet its etiology remains obscure …
better predicts disease outcome than plasma viral load, yet its etiology remains obscure …
Interleukin-6 in biology and medicine
S Akira, T Taga, T Kishimoto - Advances in immunology, 1993 - Elsevier
Publisher Summary This chapter focuses on structure and expression of interleukin-6 (IL-6),
which is a cytokine with pleiotropic activities that plays a central role in host defense. IL-6 …
which is a cytokine with pleiotropic activities that plays a central role in host defense. IL-6 …
Pathogenic mechanisms of HIV disease
Human immunodeficiency virus (HIV) infection is generally characterized by inefficient viral
transmission; an acute phase of intense viral replication and dissemination to lymphoid …
transmission; an acute phase of intense viral replication and dissemination to lymphoid …
Laboratory diagnosis and interpretation of tests for syphilis
SA Larsen, BM Steiner, AH Rudolph - Clinical microbiology …, 1995 - Am Soc Microbiol
The lack of a method for demonstrating the presence of Treponema pallidum by growth
necessitates the use of alternative methods. Traditionally, these methods are divided into …
necessitates the use of alternative methods. Traditionally, these methods are divided into …
B cells in HIV infection and disease
S Moir, AS Fauci - Nature Reviews Immunology, 2009 - nature.com
In recent years, intense research efforts have been dedicated to elucidating the pathogenic
mechanisms of HIV-associated disease progression. In addition to the progressive depletion …
mechanisms of HIV-associated disease progression. In addition to the progressive depletion …
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 …
ABSTRACT A window of opportunity for immune responses to extinguish human
immunodeficiency virus type 1 (HIV-1) exists from the moment of transmission through …
immunodeficiency virus type 1 (HIV-1) exists from the moment of transmission through …
Emerging concepts in the immunopathogenesis of AIDS
DC Douek, M Roederer, RA Koup - Annual review of medicine, 2009 - annualreviews.org
There is an intense interplay between HIV and the immune system, and the literature is
replete with studies describing various immunological phenomena associated with HIV …
replete with studies describing various immunological phenomena associated with HIV …
[HTML][HTML] Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and …
Elevated inflammatory cytokines (EMCs) at mucosal surfaces have been associated with
HIV susceptibility, but the underlying mechanisms remain unclear. We characterized the …
HIV susceptibility, but the underlying mechanisms remain unclear. We characterized the …