Circadian rhythms in the blood–brain barrier: impact on neurological disorders and stress responses

N Schurhoff, M Toborek - Molecular brain, 2023 - Springer
Circadian disruption has become more prevalent in society due to the increase in shift work,
sleep disruption, blue light exposure, and travel via different time zones. The circadian …

Chronotherapeutics for solid tumors

CO Kisamore, BD Elliott, AC DeVries, RJ Nelson… - Pharmaceutics, 2023 - mdpi.com
Circadian rhythms are internal manifestations of the 24-h solar day that allow for
synchronization of biological and behavioral processes to the external solar day. This …

Time of day bias for biological sampling in studies of mammary cancer

JC Walton, WH Walker, RJ Nelson, AC DeVries - Scientific Reports, 2024 - nature.com
Despite its demonstrated biological significance, time of day is a broadly overlooked
biological variable in preclinical and clinical studies. How time of day affects the influence of …

The Blood-Brain Barrier: Implications for Experimental Cancer Therapeutics

JP Straehla, DA Reardon, PY Wen… - Annual review of …, 2023 - annualreviews.org
The blood-brain barrier is critically important for the treatment of both primary and metastatic
cancers of the central nervous system (CNS). Clinical outcomes for patients with primary …

Exploring chronomodulated radiotherapy strategies in a chaotic population model

GM Ramírez-Ávila, J Kurths, D Gonze… - Chaos, Solitons & Fractals, 2023 - Elsevier
We present a simple nonlinear model describing the population dynamics of cancerous,
healthy, and effector cells submitted to ionizing radiation. We examine the situations in …

Melatonin Alters Preference to Move Toward Monochromatic Lights in Female Syrian Hamsters: A Behavior Associated With Circadian Rhythm

AF Shadman - Journal of Experimental Zoology Part A …, 2024 - Wiley Online Library
Different light colors have different effects on endogenous melatonin. The preference for
light colors has been studied in various animal species, except hamsters. Additionally, no …

Time of Day Variation in Mechanisms Underlying Social Stress

E Shaughnessy - 2024 - scholarworks.gsu.edu
Social stress is a salient risk factor for the etiology and persistence of multiple
neuropsychiatric diseases including schizophrenia, anxiety, and mood disorders and is …