Harnessing Artificial Intelligence in Multimodal Omics Data Integration: Paving the Path for the Next Frontier in Precision Medicine

Y Nam, J Kim, SH Jung, J Woerner… - Annual Review of …, 2024 - annualreviews.org
The integration of multiomics data with detailed phenotypic insights from electronic health
records marks a paradigm shift in biomedical research, offering unparalleled holistic views …

Identifying serum metabolite biomarkers for autoimmune diseases: a two-sample mendelian randomization and meta-analysis

W Wang, M Huang, W Ge, J Feng, X Zhang… - Frontiers in …, 2024 - frontiersin.org
Background Extensive evidence suggests a link between alterations in serum metabolite
composition and various autoimmune diseases (ADs). Nevertheless, the causal relationship …

Mendelian randomization study of causal link from Cerebrospinal fluid metabolomics to neurodegenerative diseases

J Zhang, X Zhang, B Xiao, J Ouyang, P Wang, X Peng - Neurogenetics, 2025 - Springer
To investigate the causal relationships between cerebrospinal fluid (CSF) metabolites and
various neurodegenerative diseases (NDDs), we conducted a two-sample Mendelian …

Evaluating metabolome-wide causal effects on risk for psychiatric and neurodegenerative disorders

L Gilchrist, J Mutz, P Hysi, C Legido-Quigley, S Koks… - medRxiv, 2024 - medrxiv.org
Evidence indicates phenotypic and biological overlap between psychiatric and
neurodegenerative disorders. Further identification of underlying mutual and unique …