A technological solution for the management of diabetes in people who require intensive
insulin therapy has been sought for decades. The last 10 years have seen substantial …

Background Closed-loop artificial pancreas systems have been in development for several
years, including assessment in numerous varied outpatient clinical trials. We aimed to …

Background The achievement of glycaemic control remains challenging for patients with
type 1 diabetes. We assessed the effectiveness of day-and-night hybrid closed-loop insulin …

Background Tight control of blood glucose in type 1 diabetes delays onset of macrovascular
and microvascular diabetic complications; however, glucose levels need to be closely …

Introduction Glycemic control in participants with insulin-treated diabetes remains
challenging. We assessed safety and efficacy of new flash glucose-sensing technology to …

Objective To evaluate the efficacy and safety of artificial pancreas treatment in non-pregnant
outpatients with type 1 diabetes. Design Systematic review and meta-analysis of …

Abstract Supplementary Table S1 Continuous Glucose Monitoring (CGM) has been
demonstrated to be clinically valuable, reducing risks of hypoglycemia and hyperglycemia …

Importance Hybrid closed-loop (HCL) therapy has improved glycemic control in children and
adolescents with type 1 diabetes; however, the efficacy of HCL on glycemic and …

OBJECTIVE To investigate glycemic and psychosocial outcomes with hybrid closed-loop
(HCL) versus user-determined insulin dosing with multiple daily injections (MDI) or insulin …

Intelligent machines using machine learning algorithms are ubiquitous, ranging from simple
data analysis and pattern recognition tools to complex systems that achieve superhuman …