Autophagy is a fundamental cellular process that eliminates molecules and subcellular
elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated …

Autophagy is an evolutionarily conserved, lysosome-dependent catabolic process whereby
cytoplasmic components, including damaged organelles, protein aggregates and lipid …

Skeletal muscle is the protein reservoir of our body and an important regulator of glucose
and lipid homeostasis. Consequently, the growth or the loss of muscle mass can influence …

Sarcopenia represents a muscle-wasting syndrome characterized by progressive and
generalized degenerative loss of skeletal muscle mass, quality, and strength occurring …

Frailty, a consequence of the interaction of the aging process and certain chronic diseases,
compromises functional outcomes in the elderly and substantially increases their risk for …

Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

Autophagy is a conserved process that catabolizes intracellular components to maintain
energy homeostasis and to protect cells against stress. Autophagy has crucial roles during …

The maintenance of mitochondrial integrity is critical for muscle health. Mitochondria,
indeed, play vital roles in a wide range of cellular processes, including energy supply, Ca2+ …

Macroautophagy (autophagy) is a conserved lysosomal degradation process essential for
cellular homeostasis and adaption to stress. Accumulating evidence indicates that …