Idiopathic membranous nephropathy (INM) remains a common cause of the nephrotic
syndrome in adults. The autoimmune nature of IMN was clearly delineated in 2009 with the …

Renal aging, by itself, is associated with alterations in renal morphology and a decline in
renal function, which is accelerated and/or accentuated by diseases such as diabetes …

BACKGROUND: The prevalence of elderly individuals continues to increase over time, as
does the incidence of acute kidney injury (AKI). However, it is not known whether age is an …

Owing to advances in modern medicine, life expectancies are lengthening and leading to an
increase in the population of older individuals. The aging process leads to significant …

Tumor lysis syndrome is a metabolic complication that may follow the initiation of cancer
therapy. It commonly occurs in hematological malignant patients particularly non‐Hodgkin's …

Three decades have passed since a series of studies indicated that the aging kidney was
characterized by increased susceptibility to nephrotoxic injury. Data from these experimental …

In people who are aged> 65 years, pharmacokinetics are influenced more by the loss of
kidney function than by the aging process of any other organ. A GFR of 30 to 60 ml/min …

Tumor lysis syndrome is an oncometabolic emergency resulting from rapid cell death. Tumor
lysis syndrome can occur as a consequence of tumor targeted therapy or spontaneously …

The aging kidney undergoes a number of important anatomic and physiologic changes that
increase the risk of acute kidney injury (formerly acute renal failure) in the elderly. This …

Introduction: The worldwide population is aging, and several age-associated physiological
and pathophysiological changes can affect drug disposition. This is particularly important in …