The human genome encodes 538 protein kinases that transfer a γ-phosphate group from
ATP to serine, threonine, or tyrosine residues. Many of these kinases are associated with …

Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

An important hallmark in cancer cells is the increase in glucose uptake. GLUT1 is an
important target in cancer treatment because cancer cells upregulate GLUT1, a membrane …

Abstract Background Resveratrol (3, 5, 4′‐trihydroxystilbene), a natural polyphenol and
phytoalexin, has drawn considerable attention in the past decade due to its wide variety of …

Cancer is one of the leading causes of death worldwide. Chemotherapy and radiotherapy
are the conventional primary treatments for cancer patients. However, most of cancer cells …

In addition to thousands of research papers related to resveratrol (RSV), approximately 300
review articles have been published. Earlier research tended to focus on pharmacological …

Cancer is a major factor threatening human health and life safety, and there is a lack of safe
and effective therapeutic drugs. Intervention and prevention in premalignant process are …

Stilbenes are a class of polyphenolic compounds, naturally found in a wide variety of dietary
sources such as grapes, berries, peanuts, red wine, and some medicinal plants. There are …

Prostate cancer is the most commonly diagnosed cancer disease in men in the Unites States
and its management remains a challenge in everyday oncology practice. Thus, advanced …