Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the
circulation of multiple serotypes, global expansion of the disease and recent gains in …

Mast cells (MCs), which are granulated tissue-resident cells of hematopoietic lineage,
contribute to vascular homeostasis, innate/adaptive immunity, and wound healing. However …

Dendritic cells (DCs) of the cDC2 lineage initiate allergic immunity and in the dermis are
marked by their expression of CD301b. CD301b+ dermal DCs respond to allergens …

The urinary tract is constantly exposed to microorganisms that inhabit the gastrointestinal
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …

Although mast cells were discovered more than a century ago, their functions beyond their
role in allergic responses remained elusive until recently. However, there is a growing …

Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …

Mast cells are multifunctional cells that initiate not only IgE-dependent allergic diseases but
also play a fundamental role in innate and adaptive immune responses to microbial …

Cytokine storm syndrome is a cascade of escalated immune responses disposing the
immune system to exhaustion, which might ultimately result in organ failure and fatal …

Mast cells (MCs), which are granulated tissue-resident cells of hematopoietic lineage,
constitute a major sensory arm of the innate immune system. In this review we discuss the …

Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and
autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and …