Mechanistic insights into human brain impact dynamics through modal analysis

K Laksari, M Kurt, H Babaee, S Kleiven, D Camarillo - Physical review letters, 2018 - APS
Although concussion is one of the greatest health challenges today, our physical
understanding of the cause of injury is limited. In this Letter, we simulated football head …

ECOGEN: An open-source tool for multiphase, compressible, multiphysics flows

K Schmidmayer, F Petitpas, S Le Martelot… - Computer Physics …, 2020 - Elsevier
ECOGEN, a new open-source computational fluid dynamics code is presented. It is a multi-
model tool devoted to the simulation of compressible flows. A large range of problems can …

A knowledge map analysis of brain biomechanics: Current evidence and future directions

F Eskandari, M Shafieian, MM Aghdam, K Laksari - Clinical Biomechanics, 2020 - Elsevier
Although brain, one of the most complex organs in the mammalian body, has been
subjected to many studies from physiological and pathological points of view, there remain …

Tension strain-softening and compression strain-stiffening behavior of brain white matter

F Eskandari, M Shafieian, MM Aghdam… - Annals of Biomedical …, 2021 - Springer
Brain, the most important component of the central nervous system (CNS), is a soft tissue
with a complex structure. Understanding the role of brain tissue microstructure in mechanical …

Structural anisotropy vs. mechanical anisotropy: the contribution of axonal fibers to the material properties of brain white matter

F Eskandari, M Shafieian, MM Aghdam… - Annals of biomedical …, 2021 - Springer
Brain's micro-structure plays a critical role in its macro-structure material properties. Since
the structural anisotropy in the brain white matter has been introduced due to axonal fibers …

Multi-directional dynamic model for traumatic brain injury detection

K Laksari, M Fanton, LC Wu, TH Nguyen… - Journal of …, 2020 - liebertpub.com
Given the worldwide adverse impact of traumatic brain injury (TBI) on the human population,
its diagnosis and prediction are of utmost importance. Historically, many studies have …

MFC: An open-source high-order multi-component, multi-phase, and multi-scale compressible flow solver

SH Bryngelson, K Schmidmayer, V Coralic… - Computer Physics …, 2021 - Elsevier
MFC is an open-source tool for solving multi-component, multi-phase, and bubbly
compressible flows. It is capable of efficiently solving a wide range of flows, including droplet …

Nonlinear dynamical behavior of the deep white matter during head impact

J Abderezaei, W Zhao, CL Grijalva, G Fabris, S Ji… - Physical Review …, 2019 - APS
Traumatic brain injury (TBI) is a major public health concern, affecting as many as 3 million
people each year in the US Despite substantial research efforts in recent years, our physical …

The effect of large deformation on Poisson's ratio of brain white matter: An experimental study

F Eskandari, Z Rahmani… - Proceedings of the …, 2021 - journals.sagepub.com
A more Accurate description of the mechanical behavior of brain tissue could improve the
results of computational models. While most studies have assumed brain tissue as an …

Optimization of a multifrequency magnetic resonance elastography protocol for the human brain

M Kurt, L Wu, K Laksari, E Ozkaya… - Journal of …, 2019 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE The brain's stiffness measurements from
magnetic resonance elastography (MRE) strongly depend on actuation frequencies, which …