Idiopathic nephrotic syndrome is the most frequent pediatric glomerular disease, affecting
from 1.15 to 16.9 per 100,000 children per year globally. It is characterized by massive …

Abstract The 2012 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice
guideline on glomerulonephritis (GN) is intended to assist the practitioner caring for patients …

Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Background: The contemporary management of ambulatory ulcerative colitis (UC) continues
to be challenging with∼ 20% of children needing a colectomy within childhood years. We …

Objective: To frame revised guidelines on diagnosis, evaluation, management, and
supportive care of patients with the illness. Process: The guidelines combine evidence …

Background Scarce data are available on the use of vedolizumab in children with
inflammatory bowel disease (IBD). We aimed to evaluate the safety, effectiveness, and …

This consensus document is aimed at providing an updated, multidisciplinary overview on
the diagnosis and treatment of pediatric nephrotic syndrome (NS) at first presentation. It is …

Background Vedolizumab, an anti-integrin antibody, has proven to be effective in adults with
inflammatory bowel disease [IBD], but the data in paediatrics are limited. We describe the …

Steroid-sensitive nephrotic syndrome (SSNS) is a rare condition that develops primarily in
preadolescent children after the age of 1 year. Since the 1950s, oral corticosteroids have …

Introduction The optimal trial design for assessing novel therapies in paediatric IBD (PIBD) is
a subject of intense ongoing global discussions and debate among the different …