Cytokines and their relationship to the symptoms and outcome of cancer

B Seruga, H Zhang, LJ Bernstein, IF Tannock - Nature Reviews Cancer, 2008 - nature.com
Tumours contain immune cells and a network of pro-and anti-inflammatory cytokines, which
collaborate in the development and progression of cancer. Cytokine profiles might prove to …

Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements

KSA Khabar - Cellular and molecular life sciences, 2010 - Springer
A considerable number of genes that code for AU-rich mRNAs including cytokines, growth
factors, transcriptional factors, and certain receptors are involved in both chronic …

Genetic aspects of inflammation and cancer

GL Hold, ME El-Omar - Biochemical Journal, 2008 - portlandpress.com
Chronic inflammation is involved in the pathogenesis of most common cancers. The
aetiology of the inflammation is varied and includes microbial, chemical and physical …

Association between Interferon-Lambda-3 rs12979860, TLL1 rs17047200 and DDR1 rs4618569 Variant Polymorphisms with the Course and Outcome of SARS …

SHA Agwa, MM Kamel, H Elghazaly, AM Abd Elsamee… - Genes, 2021 - mdpi.com
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
provides a critical host-immunological challenge. Aim: We explore the effect of host-genetic …

Novel insights into miR-944 in cancer

J Shen, Q Wang, C Liang, X Su, Y Ke, Y Mao, J Fang… - Cancers, 2022 - mdpi.com
Simple Summary miR-944 is localized in intron 4 of TP63. ΔNp63 in intron 3 of TP63 recruits
the transcription factor AP-2 to promote miR-944 gene expression, which mediates …

Cognitive dysfunction among cancer survivors

A Asher - American journal of physical medicine & rehabilitation, 2011 - journals.lww.com
Cognitive dysfunction among cancer survivors, commonly referred to as" chemobrain," has
gained increased attention in the last decade. Cognitive dysfunction is now well recognized …

Influence of interleukin-8 and interleukin-10 on sporadic colon cancer development and progression

T Čačev, S Radošević, Š Križanac… - …, 2008 - academic.oup.com
Cytokines produced in the tumour microenvironment have an important role in cancer
pathogenesis. Altered cytokine expression may result in increased susceptibility to and/or …

COX-2 is overexpressed in primary prostate cancer with metastatic potential and may predict survival. A comparison study between COX-2, TGF-β, IL-10 and Ki67

E Richardsen, RD Uglehus, J Due, C Busch… - Cancer …, 2010 - Elsevier
Background: The immune modulating molecules cyclooxygenase-2 (COX-2), transforming
growth factor-β (TGF-β) and interleukin-10 (IL-10) have regulatory roles in cancer …

[HTML][HTML] NLRP3 inflammasome activation plays a carcinogenic role through effector cytokine IL-18 in lymphoma

X Zhao, C Zhang, M Hua, R Wang, C Zhong, J Yu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Inflammasomes play important roles in the pathogenesis of tumors, but the roles of NLRP3
inflammasome in the lymphoma remain unclear. Activated NLRP3 inflammasome induces …

The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC

NJ Liptrott, M Penny, PG Bray, J Sathish… - British journal of …, 2009 - Wiley Online Library
Mandarin translation of abstract Background and purpose: The function of transporters in
peripheral blood mononuclear cells (PBMC) has been characterized, but less is known …