Cardiac troponin is the most effective translational safety biomarker for myocardial injury in cardiotoxicity

PJ O'Brien - Toxicology, 2008 - Elsevier
There is an overwhelming weight of evidence that certifies cardiac troponin (cTn) as the
preferred, defacto, translational, safety biomarker for myocardial injury in cardiotoxicity. As …

A systematic comparison of exercise training protocols on animal models of cardiovascular capacity

R Feng, L Wang, Z Li, R Yang, Y Liang, Y Sun, Q Yu… - Life sciences, 2019 - Elsevier
Cardiovascular disease (CVD) is a major global cause of mortality, which has prompted
numerous studies seeking to reduce the risk of heart failure and sudden cardiac death …

Validity and reliability of Polar® RS800CX heart rate monitor, measuring heart rate in dogs during standing position and at trot on a treadmill

A Essner, R Sjöström, E Ahlgren, B Lindmark - Physiology & behavior, 2013 - Elsevier
The aim of the present study was to assess criterion validity, and relative and absolute
reliability of Polar® RS800CX heart rate monitor, compared to simultaneously recorded …

Effect of moderate treadmill exercise on some physiological parameters in untrained beagle dogs

G Piccione, S Casella, M Panzera, C Giannetto… - Experimental …, 2012 - jstage.jst.go.jp
The aim of the present study was to evaluate the modifications of some physiological
parameters during moderate treadmill exercise in seven healthy Beagle dogs. All animals …

Evaluation of new and old biomarkers in dogs with degenerative mitral valve disease

S Klein, I Nolte, JL Granados-Soler, P Lietz… - BMC veterinary …, 2022 - Springer
Background Dogs with degenerative mitral valve disease are commonly presented to small
animal clinicians. Diagnosis, clinical staging, and therapeutic design are based on a …

Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs

JA Cerqueira, WAZ Restan, MG Fonseca… - Research in veterinary …, 2018 - Elsevier
Few data exist on the physiological consequences of an incremental exercise test (IET) and
training in dogs. Here we evaluated the effect of an endurance-training program (ETP) on …

Reliability of an incremental exercise test to evaluate acute blood lactate, heart rate and body temperature responses in Labrador retrievers

L Ferasin, S Marcora - Journal of Comparative Physiology B, 2009 - Springer
Thirteen healthy Labrador retrievers underwent a 5-stage incremental treadmill exercise test
to assess its reliability. Blood lactate (BL), heart rate (HR), and body temperature (BT) were …

Investigation of the cardiac effects of exercise testing on apparently healthy Boxer dogs

D Agarwal, E Côté, L O'Sullivan… - Journal of Veterinary …, 2023 - Wiley Online Library
Background Holter electrocardiographic monitoring is a cornerstone of diagnostic testing for
arrhythmogenic cardiomyopathy (ACM) in Boxer dogs, but physical activity during …

Clinical use of submaximal treadmill exercise testing and assessments of cardiac biomarkers NT-proBNP and cTnI in dogs with presymptomatic mitral regurgitation

L Wall, A Mohr, FL Ripoli, N Schulze, CD Penter… - PloS one, 2018 - journals.plos.org
Exercise intolerance is the first symptom of heart disease. Yet an objective and standardised
method in canine cardiology to assess exercise capacity in a clinical setting is lacking. In …

The effect of the surgical treatment of brachycephalic obstructive airway syndrome on the thermoregulatory response to exercise in French bulldogs: a pilot study

Ž Žgank, A Nemec Svete, H Lenasi… - Frontiers in veterinary …, 2023 - frontiersin.org
Introduction Due to altered anatomy of the upper respiratory tract, brachycephalic dogs
exhibit increased airway resistance and reduced surface area for evaporative heat loss …