Oxidative stress and the role of redox signalling in chronic kidney disease

S Kishi, H Nagasu, K Kidokoro… - Nature Reviews …, 2024 - nature.com
Chronic kidney disease (CKD) is a major public health concern, underscoring a need to
identify pathogenic mechanisms and potential therapeutic targets. Reactive oxygen species …

[HTML][HTML] Macula Densa Nitric Oxide Synthase-1 Controls Renin Release and Renin-Dependent Blood Pressure Changes

C Liu, X Wang, C Parris, Q Pang, MU Naeem… - Discovery …, 2023 - ncbi.nlm.nih.gov
Background: The function of macula densa nitric oxide synthase 1 (NOS1) in the regulation
of renin release is controversial. This study was conducted to further elucidate the role of …

A contemporary view of the macula densa: kidney remodeling

SJ Shankland, JW Pippin, O Wessely - Kidney International, 2025 - kidney-international.org
A high salt intake has deleterious effects on blood pressure and kidney function in patients
with chronic kidney disease (CKD), compelling a low salt diet as a critical non …

Matrix Metalloproteinase 2 is crucial for hypertension-and hyperglycemia-induced kidney injury independent of blood pressure

R Liu, A Staruschenko - Journal of Cardiovascular Pharmacology, 2022 - journals.lww.com
In the United States, kidney diseases are a leading cause of death. According to the Center
for Disease Control and Prevention, approximately 37 million US adults are estimated to …