Cotrimoxazole guidelines for infants who are HIV-exposed but uninfected: a call for a public health and ethics approach to the evidence

B Daniels, L Kuhn, E Spooner, H Mulol… - The Lancet Global …, 2022 - thelancet.com
WHO first recommended cotrimoxazole prophylaxis for all infants who are HIV-exposed but
uninfected (HEU) in 2000, given the ability of this treatment to prevent mortality from …

High burden and seasonal variation of paediatric scabies and pyoderma prevalence in The Gambia: A cross-sectional study

EP Armitage, E Senghore, S Darboe… - PLoS neglected …, 2019 - journals.plos.org
Background Scabies is a WHO neglected tropical disease common in children in low-and
middle-income countries. Excoriation of scabies lesions can lead to secondary pyoderma …

Biannual azithromycin distribution and child mortality among malnourished children: a subgroup analysis of the MORDOR cluster-randomized trial in Niger

KS O'Brien, AM Arzika, R Maliki, F Manzo… - PLoS …, 2020 - journals.plos.org
Background Biannual azithromycin distribution has been shown to reduce child mortality as
well as increase antimicrobial resistance. Targeting distributions to vulnerable subgroups …

Empowering local research ethics review of antibacterial mass administration research

NK Sewankambo, P Kutyabami - Infectious Diseases of Poverty, 2022 - mednexus.org
Background: Recent studies using mass drug administration (MDA) of antibiotics to entire
communities have focused global attention on the unique ethical challenges of MDA of …

Ethical challenges in mass drug administration for reducing childhood mortality: a qualitative study

A Alasmar, AC Kong, AD So, M DeCamp - Infectious Diseases of Poverty, 2022 - Springer
Background Mass drug administration (MDA) of medications to entire at-risk communities or
populations has shown promise in the control and elimination of global infectious diseases …

Age-based targeting of biannual azithromycin distribution for child survival in Niger: an adaptive cluster-randomized trial protocol (AVENIR)

KS O'Brien, AM Arzika, A Amza, R Maliki, S Ousmane… - BMC Public Health, 2021 - Springer
Background Biannual distribution of azithromycin to children 1–59 months old reduced
mortality by 14% in a cluster-randomized trial. The World Health Organization has proposed …

Priorities in reducing child mortality: Azithromycin and other interventions

D Mabey, U Okomo, B Greenwood - Plos Medicine, 2020 - journals.plos.org
Priorities in reducing child mortality: Azithromycin and other interventions | PLOS Medicine Skip
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Projected impact and cost-effectiveness of community-based versus targeted azithromycin administration strategies for reducing child mortality in sub-Saharan Africa

RL Brander, MR Weaver, PB Pavlinac… - Clinical Infectious …, 2022 - academic.oup.com
Background Trials of mass drug administration (MDA) of azithromycin (AZM) report
reductions in child mortality in sub-Saharan Africa. AZM targeted to high-risk children may …

[图书][B] Improving child survival with biannual distribution of azithromycin: an exploration of optimal program design

KS O'Brien - 2020 - search.proquest.com
Abstract The Sustainable Development Goals (SDG) aim to eliminate preventable child
mortality by 2030. Despite the notable improvement in child survival in sub-Saharan Africa in …

Addressing adverse outcomes following acute illness among children in Sub-Saharan Africa: predicting risks and cost-effectiveness

R Brander - 2019 - digital.lib.washington.edu
Children under age 5 in sub-Saharan Africa suffer a disproportionately high burden of
infections disease, and the consequences of these conditions extend beyond the period …