Crosstalk between dysfunctional mitochondria and inflammation in glaucomatous neurodegeneration

AH Jassim, DM Inman, CH Mitchell - Frontiers in pharmacology, 2021 - frontiersin.org
Mitochondrial dysfunction and excessive inflammatory responses are both sufficient to
induce pathology in age-dependent neurodegenerations. However, emerging evidence …

[HTML][HTML] Natural products for the treatment of age-related macular degeneration: new insights focusing on mitochondrial quality control and cGAS/STING pathway

X Xie, S Lian, W Yang, S He, J He, Y Wang… - Journal of …, 2024 - Elsevier
Age-related macular degeneration (AMD) is a disease that affects the vision of elderly
individuals worldwide. Although current therapeutics have shown effectiveness against …

The cGAS–STING pathway in diabetic retinopathy and age-related macular degeneration

B Hu, JX Ma, AS Duerfeldt - Future Medicinal Chemistry, 2023 - Taylor & Francis
Diabetic retinopathy and age-related macular degeneration are common retinal diseases
with shared pathophysiology, including oxidative stress-induced inflammation. Cellular …