Plasma high density lipoproteins (HDL) are small, dense, protein-rich particles compared
with other lipoprotein classes; roughly half of total HDL mass is accounted for by lipid …

High density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart
disease, and HDL exerts various potentially antiatherogenic properties, including the …

HDL is a major atheroprotective factor, but the mechanisms underlying this effect are still
obscure. HDL binding to scavenger receptor-BI has been shown to activate eNOS, although …

The inverse correlation between serum levels of high density lipoprotein (HDL) cholesterol
and the risk of coronary heart disease, the protection of susceptible animals from …

Apoptotic cell death following injury of vascular endothelium is assumed to play an important
role in the pathogenesis of atherosclerosis. In this report, we demonstrate that high density …

Observational studies provide overwhelming evidence that a low high-density lipoprotein
(HDL)–cholesterol level increases the risk of coronary events, both in healthy subjects and …

Objective—Plasma high-density lipoprotein (HDL) level is inversely correlated with the risk
of atherosclerosis. However, the cellular mechanism by which HDL exerts antiatherogenic …

Sphingosine 1-phosphate (S1P) concentration in plasma and serum has been estimated to
be within 200–900 nM. Among plasma and serum components, S1P is concentrated in …

Elevated plasma levels of HDL cholesterol or apolipoprotein AI, the major protein moiety of
HDL particles, are protective against coronary artery disease. HDL particles remove …

Sphingolipids in general and ceramides in particular, contribute to pathophysiological
mechanisms by modifying signalling and metabolic pathways. Here, we present the …