Optimal fracture treatment requires knowledge of the complex physiological process of bone
healing. The course of bone healing is mainly influenced by fracture fixation stability …

Complications in treatment of large bone defects using bone grafting still remain. Our
understanding of the endogenous bone regeneration cascade has inspired the exploration …

Small animal fracture models have gained increasing interest in fracture healing studies. To
achieve standardized and defined study conditions, various variables must be carefully …

Background Degradable magnesium implants are promising for clinical fracture treatment,
providing less stress-shielding mechanical support and superior bone-strengthening …

Background and purpose—Constant fixator stiffness for the duration of healing may not
provide suitable mechanical conditions for all stages of bone repair. We therefore …

In poly‐traumatic patients a blunt chest trauma is an important trigger of the posttraumatic
systemic inflammatory response. There is clinical evidence that fracture healing is delayed …

Objectives: This study evaluated the effect of late dynamization on callus stiffness and size in
a rat diaphyseal femoral osteotomy model. It was hypothesized that late dynamization, after …

BACKGROUND We recently demonstrated that a blunt chest trauma, a strong inducer of the
posttraumatic systemic inflammatory response and one of the most critical injuries in …

During bone healing, tissue formation processes are governed by mechanical strain.
Sost/sclerostin, a key Wnt signaling inhibitor and mechano‐sensitive pathway, is …

The rat is of increasing importance for experimental studies on fracture healing. The healing
outcome of long bone fractures is strongly influenced by mechanical factors, such as the …