The novel coronavirus SARS-CoV-2 enters into the human body mainly through the ACE2+
TMPRSS2+ nasal epithelial cells. The initial host response to this pathogen occurs in a …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the causative agent of
coronavirus disease 2019 (COVID‐19), has caused millions of deaths in the past two years …

The inflammatory and IFN pathways of innate immunity play a key role in the resistance and
pathogenesis of coronavirus disease 2019 (COVID-19). Innate sensors and SARS-CoV-2 …

COVID-19, caused by SARS-CoV-2 virus, emerged as a pandemic disease posing a severe
threat to global health. To date, sporadic studies have demonstrated that innate immune …

In addition to the respiratory system, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …

Background SARS-CoV-2 has been responsible for considerable mortality worldwide, owing
in particular to pulmonary failures such as ARDS, but also to other visceral failures and …

Severe acute respiratory syndrome (SARS)-CoV-2 infection leads to severe disease
associated with cytokine storm, vascular dysfunction, coagulation, and progressive lung …

Whilst the majority of individuals infected with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19, experience mild to …

Abstract During SARS-CoV-2 infection, the innate immune response can be inhibited or
delayed, and the subsequent persistent viral replication can induce emergency signals that …

Background Emerging evidence argues that monocytes, circulating innate immune cells, are
principal players in COVID-19 pneumonia. The study aimed to investigate the role of soluble …