The role of inflammation in diabetic retinopathy

JV Forrester, L Kuffova, M Delibegovic - Frontiers in immunology, 2020 - frontiersin.org
Inflammation is central to pathogenic processes in diabetes mellitus and the metabolic
syndrome and particularly implicates innate immunity in the development of complications …

Diabetic macular edema: current understanding, molecular mechanisms and therapeutic implications

J Zhang, J Zhang, C Zhang, J Zhang, L Gu, D Luo… - Cells, 2022 - mdpi.com
Diabetic retinopathy (DR), with increasing incidence, is the major cause of vision loss and
blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the …

Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy

L Tang, GT Xu, JF Zhang - Neural regeneration research, 2023 - journals.lww.com
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease,
is the leading cause of visual impairment in diabetic patients. Many clinical features …

Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy

J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

[PDF][PDF] Inflammatory and angiogenic biomarkers in diabetic retinopathy

S Kaštelan, I Orešković, F Bišćan, H Kaštelan… - Biochemia …, 2020 - hrcak.srce.hr
Review Page 1 Abstract Diabetic retinopathy (DR) is one of the most common microvascular
complications of diabetes mellitus (DM) and a leading cause of blindness in working-age …

[HTML][HTML] The cells involved in the pathological process of diabetic retinopathy

S Yang, J Zhang, L Chen - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetic retinopathy (DR) is an expanding global health problem, the exact mechanism of
which has not yet been clarified clearly, new insights into retinal physiology indicate that …

Studies of the retinal microcirculation using human donor eyes and high-resolution clinical imaging: insights gained to guide future research in diabetic retinopathy

C Balaratnasingam, D An, M Hein, P Yu… - Progress in Retinal and …, 2023 - Elsevier
The microcirculation plays a key role in delivering oxygen to and removing metabolic wastes
from energy-intensive retinal neurons. Microvascular changes are a hallmark feature of …

Long noncoding RNA MIAT regulates primary human retinal pericyte pyroptosis by modulating miR-342–3p targeting of CASP1 in diabetic retinopathy

X Yu, X Ma, W Lin, Q Xu, H Zhou, HY Kuang - Experimental eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is the leading cause of visual impairment and acquired blindness
among adults worldwide. Retinal microvascular pericyte deficiency is one of the earliest …

Pyroptosis in the retinal neurovascular unit: new insights into diabetic retinopathy

C Meng, C Gu, S He, T Su, T Lhamo, D Draga… - Frontiers in …, 2021 - frontiersin.org
Diabetic retinopathy (DR) is prevalent among people with long-term diabetes mellitus (DM)
and remains the leading cause of visual impairment in working-aged people. DR is related …

Intravitreal anti-vascular endothelial growth factor agents for the treatment of diabetic retinopathy: a review of the literature

I Chatziralli, A Loewenstein - Pharmaceutics, 2021 - mdpi.com
Background: Diabetic retinopathy (DR) is the leading cause of blindness in the working-age
population. The purpose of this review is to gather the existing literature regarding the use of …