Simple Summary Novel therapeutic targets are needed to improve treatments of aggressive
cancers and viral diseases. Tetraspanins represent an emerging class of anticancer targets …

Contact inhibition (CI) represents a crucial tumor-suppressive mechanism responsible for
controlling the unbridled growth of cells, thus preventing the formation of cancerous tissues …

To promote the potential of arachidonic acid (ARA) for cancer prevention and management,
experiments were implemented to disclose the mechanisms of its tumoricidal action …

Tight junctions regulate epithelial barrier function and have been shown to be influenced by
multiple classes of proteins. Apical integrins have been identified as potential regulators of …

Cell-cell contact formation of polarized epithelial cells is a multi-step process that involves
the co-ordinated activities of Rho family small GTPases. Consistent with the central role of …

Entosis is a cell competition process during which tumor cells engulf other tumor cells. It is
initiated by metabolic stress or by loss of matrix adhesion, and it provides the winning cell …

Collective cellular invasion in malignant tumours is typically characterized by the
cooperative migration of multiple cells in close proximity to each other. Follower cells are led …

Mood disorders, such as depression, anxiety, addiction, and bipolar disorder, represent
significant public health concerns due to their prevalence and impact on quality of life …

We present a protocol for using micropatterns to study post-collision locomotion and entosis
of human and canine cells in vitro. We describe steps for lentiviral transduction and the …

Contact inhibition (CI) represents a crucial tumor-suppressive mechanism responsible for
controlling the unbridled growth of cells, thus preventing the formation of cancerous tissues …