Macrophage polarization in physiological and pathological pregnancy

Y Yao, XH Xu, L Jin - Frontiers in immunology, 2019 - frontiersin.org
The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …

Endoplasmic reticulum stress and homeostasis in reproductive physiology and pathology

E Guzel, S Arlier, O Guzeloglu-Kayisli… - International journal of …, 2017 - mdpi.com
The endoplasmic reticulum (ER), comprises 60% of the total cell membrane and interacts
directly or indirectly with several cell organelles ie, Golgi bodies, mitochondria and …

The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding

F Schatz, O Guzeloglu-Kayisli, S Arlier… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Human pregnancy requires robust hemostasis to prevent hemorrhage
during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification …

hCG: biological functions and clinical applications

C Nwabuobi, S Arlier, F Schatz… - International journal of …, 2017 - mdpi.com
Human chorionic gonadotropin (hCG) is produced primarily by differentiated
syncytiotrophoblasts, and represents a key embryonic signal that is essential for the …

Features of human decidual NK cells in healthy pregnancy and during viral infection

N Jabrane-Ferrat - Frontiers in immunology, 2019 - frontiersin.org
The hallmark of human early pregnancy is the accumulation of a unique population of
Natural Killer (dNK) cells at the main maternal-fetal interface, the decidua basalis. dNK cells …

H1N1 influenza virus infection results in adverse pregnancy outcomes by disrupting tissue-specific hormonal regulation

EQ Littauer, ES Esser, OQ Antao, EV Vassilieva… - PLoS …, 2017 - journals.plos.org
Increased susceptibility to influenza virus infection during pregnancy has been attributed to
immunological changes occurring before and during gestation in order to “tolerate” the …

The trophoblast plug during early pregnancy: a deeper insight

G Weiss, M Sundl, A Glasner, B Huppertz… - Histochemistry and cell …, 2016 - Springer
During the first trimester of pregnancy, foetal endovascular trophoblasts invade into maternal
spiral arteries, accumulate and form plugs in the lumen of the vessels. These plugs only …

Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and …

TT Piltonen, JC Chen, M Khatun… - Human …, 2015 - academic.oup.com
STUDY QUESTION Do endometrial stromal fibroblasts (eSF) in women with polycystic ovary
syndrome (PCOS)(eSFpcos) exhibit altered estrogen and/or progesterone (P4) responses …

Immune mechanisms linking obesity and preeclampsia

FT Spradley, AC Palei, JP Granger - Biomolecules, 2015 - mdpi.com
Preeclampsia (PE) is characterized by hypertension occurring after the twentieth week of
pregnancy. It is a significant contributor to maternal and perinatal morbidity and mortality in …

The function of decidua natural killer cells in physiology and pathology of pregnancy

F Jin, W Liu, G Cheng, S Cai, T Yin… - American Journal of …, 2023 - Wiley Online Library
The role of decidual natural killer (dNK) cells in maintaining immune tolerance at the
maternal‐fetal interface during pregnancy is a significant topic in reproductive health …