J Joffre, J Hellman, C Ince… - American journal of …, 2020 - atsjournals.org
Endothelial cells (ECs) are vascular, nonconventional immune cells that play a major role in the systemic response after bacterial infection to limit its dissemination. Triggered by …
T Iba, JH Levy - Journal of Thrombosis and Haemostasis, 2019 - Elsevier
The vascular endothelial surface is coated by the glycocalyx, a ubiquitous gel‐like layer composed of a membrane‐binding domain that contains proteoglycans, glycosaminoglycan …
BF Becker, M Jacob, S Leipert… - British journal of …, 2015 - Wiley Online Library
The endothelial glycocalyx has a profound influence at the vascular wall on the transmission of shear stress, on the maintenance of a selective permeability barrier and a low hydraulic …
EP Schmidt, Y Yang, WJ Janssen, A Gandjeva… - Nature medicine, 2012 - nature.com
Sepsis, a systemic inflammatory response to infection, commonly progresses to acute lung injury (ALI), an inflammatory lung disease with high morbidity. We postulated that sepsis …
The endothelial glycocalyx is a gel-like layer on the luminal side of blood vessels that is composed of glycosaminoglycans and the proteins that tether them to the plasma …
H Kolářová, B Ambrůzová… - Mediators of …, 2014 - Wiley Online Library
The glycocalyx of the endothelium is an intravascular compartment that creates a barrier between circulating blood and the vessel wall. The glycocalyx is suggested to play an …
Inflammation is a complex and potentially life-threatening condition that involves the participation of a variety of chemical mediators, signaling pathways, and cell types. The …
X Wang, Y Shen, M Shang, X Liu… - Cardiovascular …, 2023 - academic.oup.com
Cardiovascular disease (CVD) is a serious health challenge, causing more deaths worldwide than cancer. The vascular endothelium, which forms the inner lining of blood …
LN Broekhuizen, BA Lemkes, HL Mooij, MC Meuwese… - Diabetologia, 2010 - Springer
Aims/hypothesis Endothelial glycocalyx perturbation contributes to increased vascular permeability. In the present study we set out to evaluate whether:(1) glycocalyx is perturbed …