Knowledge gaps that hamper prevention and control of Mycobacterium avium subspecies paratuberculosis infection

HW Barkema, K Orsel, SS Nielsen… - Transboundary and …, 2018 - Wiley Online Library
In the last decades, many regional and country‐wide control programmes for Johne's
disease (JD) were developed due to associated economic losses, or because of a possible …

Development of vaccines to Mycobacterium avium subsp. paratuberculosis infection

HT Park, HS Yoo - Clinical and experimental vaccine …, 2016 - synapse.koreamed.org
Johne's disease or paratuberculosis is a chronic debilitating disease in ruminants caused by
Mycobacterium avium subsp. paratuberculosis (MAP). The disease causes significant …

A single dose polyanhydride-based nanovaccine against paratuberculosis infection

A Thukral, K Ross, C Hansen, Y Phanse… - npj Vaccines, 2020 - nature.com
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) causes Johne's
disease in ruminants and is characterized by chronic gastroenteritis leading to heavy …

A protective vaccine against Johne's disease in cattle

Y Phanse, CW Wu, AJ Venturino, C Hansen, K Nelson… - Microorganisms, 2020 - mdpi.com
Johne's disease (JD) caused by Mycobacterium avium subsp. paratuberculosis (M.
paratuberculosis) is a chronic infection characterized by the development of granulomatous …

Superior protection from live-attenuated vaccines directed against Johne's disease

DC Shippy, JJ Lemke, A Berry, K Nelson… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) is the etiological agent
of Johne's disease in ruminants. Johne's disease is an important enteric infection causing …

Preclinical models of nontuberculous mycobacteria infection for early drug discovery and vaccine research

E Rampacci, V Stefanetti, F Passamonti… - Pathogens, 2020 - mdpi.com
Nontuberculous mycobacteria (NTM) represent an increasingly prevalent etiology of soft
tissue infections in animals and humans. NTM are widely distributed in the environment and …

Peripheral IFN-ɣ production after blood stimulation with different mycobacterial antigens in goats vaccinated against paratuberculosis

M Fernández, M Royo, N Arteche-Villasol, MC Ferreras… - Vaccines, 2022 - mdpi.com
Vaccination can be an efficient method for the control of paratuberculosis in ruminants.
However, the official tuberculosis control tests cross-interfere with the animals vaccinated …

Influence of vaccination against paratuberculosis on the diagnosis of caprine tuberculosis during official eradication programmes in Castilla y León (Spain)

J Espinosa, M Fernández, M Royo… - Transboundary and …, 2021 - Wiley Online Library
The information generated from the official eradication programmes of caprine tuberculosis
(TB) in Castilla y León, Spain, during 2018, has been used to assess the effect of …

Characterization of early immune responses elicited by live and inactivated vaccines against Johne's disease in goats

M Hanafy, C Hansen, Y Phanse, C Wu… - Frontiers in Veterinary …, 2023 - frontiersin.org
Mycobacterium avium subspecies paratuberculosis (M. paratuberculosis) is the causative
agent of Johne's disease, a chronic debilitating condition affecting ruminants causing …

Reduced tissue colonization of Mycobacterium avium subsp. paratuberculosis in neonatal calves vaccinated with a cocktail of recombinant proteins

JR Stabel, JP Bannantine - Vaccine, 2021 - Elsevier
An increasing prevalence of paratuberculosis supports the need for new efficacious
vaccines as an essential management tool. Two separate studies were performed in …