[HTML][HTML] Breaking Boundaries: Immunotherapy for Myeloid Malignancies

T Gavrilova, E Schulz, A Mina - Cancers, 2024 - mdpi.com
Simple Summary Patients with myeloid malignancies (blood cancers such as leukemia and
myelodysplastic syndromes) that have returned or worsened despite chemotherapy or a …

Allogeneic hematopoietic cell transplantation in elderly patients with myelodysplastic syndromes: Considerations and challenges

E Schulz, SZ Pavletic, A Mina - Seminars in Hematology, 2024 - Elsevier
Myelodysplastic syndromes/neoplasms (MDS) and related diseases are highly
heterogeneous myeloid stem cell cancers that predominantly affect the elderly. The only …

Personalized Timing for Allogeneic Stem-Cell Transplantation in Hematologic Neoplasms: A Target Trial Emulation Approach Using Multistate Modeling and …

C Gregorio, M Spreafico, S D'Amico, E Sauta… - JCO Clinical Cancer …, 2024 - ascopubs.org
PURPOSE Decision about the optimal timing of a treatment procedure in patients with
hematologic neoplasms is critical, especially for cellular therapies (most including …

Revisiting Timing and Decision Modeling for Allogeneic Hematopoietic Stem-Cell Transplantation in Myelodysplastic Syndromes

C Cutler - Journal of Clinical Oncology, 2024 - ascopubs.org
The Oncology Grand Rounds series is designed to place original reports published in the
Journal into clinical context. A case presentation is followed by a description of diagnostic …

Hematopoietic cell transplantation (HCT) in MDS patients of older age

C Niederwieser, N Kröger - Leukemia & Lymphoma, 2024 - Taylor & Francis
Hematopoietic cell transplantation (HCT) has evolved to an essential treatment in younger
and more recently in elderly patients with myelodysplastic syndrome (MDS), the age group …

[HTML][HTML] Current challenges in conditioning regimens for MDS transplantation

AB Notarantonio, M Robin, M D'Aveni - Blood Reviews, 2024 - Elsevier
Myelodysplastic syndrome (MDS) is a very heterogeneous clonal disorder. Patients with
“higher-risk” MDS, defined by specific recurrent genetic abnormalities, have a poor …

Management of adult patients with CMML undergoing allo-HCT: recommendations from the EBMT PH&G Committee

F Onida, N Gagelmann, Y Chalandon, G Kobbe… - Blood, 2024 - ashpublications.org
Chronic myelomonocytic leukemia (CMML) is a heterogeneous disease presenting with
either myeloproliferative or myelodysplastic features. Allogeneic hematopoietic cell …

Trends in MDS and AML from ASH 2023

M Pfeilstöcker - memo-Magazine of European Medical Oncology, 2024 - Springer
Presentations in the field of clonal myeloid diseases from the 65th American Society of
Hematology conference provided insights into future therapeutic approaches especially for …

Genome sequencing in the management of myelodysplastic syndromes and related disorders

M Cazzola, L Malcovati - Haematologica, 2020 - haematologica.org
Myeloid neoplasms originate from the clonal proliferation of hematopoietic stem cells, which
is driven by the acquisition of somatic genetic mutations. Within these disorders …

[HTML][HTML] Decision Support System Defines Optimal Transplant Timing for Patients with Myelodysplastic Syndromes

A Azvolinsky - 2024 - ashpublications.org
A new clinical and genetics-based decision strategy shows how patients with low-and
moderate-low risk myelodysplastic syndromes (MDS), according to the Molecular Revised …