During pregnancy, the organization of complex tolerance mechanisms occurs to assure non-
rejection of the semiallogeneic fetus. Pregnancy is a period of vulnerability to some viral …

DNA-damaging agents and endogenous DNA damage constantly harm genome integrity.
Under genotoxic stress conditions, the DNA damage response (DDR) machinery is crucial in …

Neural stem cells (NSCs) were described for the first time more than two decades ago for
their ability to differentiate into all neural cell lineages. The isolation of NSCs from adults and …

Zika virus (ZIKV) is a mosquito-borne, single-stranded RNA virus belonging to the genus
Flavivirus. Although ZIKV infection is usually known to exhibit mild clinical symptoms …

Zika virus (ZIKV), member of the family Flaviviridae belonging to genus Flavivirus, is an
arthropod-borne virus. The ZIKV is known to cause severe congenital birth defects in …

Congenital alterations in the levels of the transcription factor Forkhead box g1 (FOXG1)
coding gene trigger" FOXG1 syndrome," a spectrum that recapitulates birth defects found in …

There are certain critical periods during pregnancy when the fetus is at high risk for
exposure to teratogens. Some microorganisms, including Toxoplasma gondii, are known to …

The Schlafen gene family encodes for proteins involved in various biological tasks, including
cell proliferation, differentiation, and T cell development. Schlafens were initially discovered …

Tick-borne encephalitis virus (TBEV) represents a pivotal tick-transmitted flavivirus
responsible for severe neurological consequences in Europe and Asia. The emergence of …

Abstract Ethnopharmacological relevance Zanthoxylum chalybeum Engl. is endemic to
Africa and has been used traditionally to treat diabetes mellitus. Moreover, its …