Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically
available and resistance can develop through de novo mutations in chromosomal genes or …

The ability to construct and maintain a structured multicellular bacterial community depends
critically on the production of extracellular matrix components (1, 2). While the biofilm matrix …

Owing to high antibiotic resistance and thermotolerance, bacterial biofilm infections (BBIs)
are refractory to elimination. Iron is essential for bacterial growth and metabolism, and …

Protein aggregation occurs as a consequence of perturbations in protein homeostasis that
can be triggered by environmental and cellular stresses. The accumulation of protein …

Bacterial proteases are an extensive collection of enzymes that have vital roles in cell
viability, stress response and pathogenicity. Although their perturbation clearly offers the …

Bacterial keratitis is a serious ocular disease that affects millions of people worldwide each
year, among which≈ 25% are caused by Staphylococcus aureus. With the spread of …

Recent progress in elucidating the role of the icaADBC-encoded polysaccharide
intercellular adhesin (PIA) or polymeric N-acetyl-glucosamine (PNAG) in staphylococcal …

Many reports have documented that Staphylococcus aureus can invade host cells and
persist intracellularly for various periods of time in cell culture models. However, it is not …

ABSTRACT A tool kit of vectors was designed to manipulate and express genes from a wide
range of gram-negative species by using in vivo recombination. Saccharomyces cerevisiae …

Bacterial biofilms cause numerous problems in health care and industry; notably, biofilms
are associated with a large number of infections. Biofilm-dwelling bacteria are particularly …