[HTML][HTML] A computational approach to design potential siRNA molecules as a prospective tool for silencing nucleocapsid phosphoprotein and surface glycoprotein …
An outbreak, caused by an RNA virus, SARS-CoV-2 named COVID-19 has become
pandemic with a magnitude which is daunting to all public health institutions in the absence …
pandemic with a magnitude which is daunting to all public health institutions in the absence …
[HTML][HTML] Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
VS Ayyagari - Journal of Genetic Engineering and Biotechnology, 2022 - Elsevier
The global COVID-19 pandemic caused by SARS-CoV2 infected millions of people and
resulted in more than 4 million deaths worldwide. Apart from vaccines and drugs, RNA …
resulted in more than 4 million deaths worldwide. Apart from vaccines and drugs, RNA …
In silico prediction of siRNA to silence the SARS-CoV-2 omicron variant targeting BA. 4, BA. 5, BQ. 1, BQ1. 1. and XBB: an alternative to traditional therapeutics
Background After the first infection in December 2019, the mutating strains of SARS-CoV2
have already affected a lot of healthy people around the world. But situations have not been …
have already affected a lot of healthy people around the world. But situations have not been …
Immunoinformatic and molecular docking approaches: siRNA prediction to silence cell surface binding protein of monkeypox virus
Background Monkeypox virus (MPV), an endemic pathogen in Africa, shares clinical
similarities with smallpox. Recent reports indicate a concerning increase in the number of …
similarities with smallpox. Recent reports indicate a concerning increase in the number of …
Exploring the potential of structural modeling and molecular docking for efficient siRNA screening: A promising approach to Combat viral mutants, with a focus on HIV …
M Nematian, Z Noormohammadi, P Rahimi… - Biochemical and …, 2024 - Elsevier
RNA interference (RNAi) holds immense potential for sequence-specific downregulation of
disease-related genes. Small interfering RNA (siRNA) therapy has made remarkable strides …
disease-related genes. Small interfering RNA (siRNA) therapy has made remarkable strides …
In vitro inhibition of replication of dengue virus serotypes 1–4 by siRNAs bound to non-toxic liposomes
CA Rodriguez-Salazar, DP Recalde-Reyes, JP Bedoya… - Viruses, 2022 - mdpi.com
Dengue virus is a ssRNA+ flavivirus, which produces the dengue disease in humans.
Currently, no specific treatment exists. siRNAs regulate gene expression and have been …
Currently, no specific treatment exists. siRNAs regulate gene expression and have been …
Strategic Design of Dicer Substrate siRNA to Mitigate the Resistance Mediated by ABCC1 in Doxorubicinresistant Breast Cancer.
AK Gatta, R Chandrashekhar… - Indian Journal of …, 2020 - search.ebscohost.com
The current study involved designing of a small interfering ribonucleic acid-loaded folate
functionalized chitosan-coated PLGA nanoparticles to evaluate tumor targeting potential in …
functionalized chitosan-coated PLGA nanoparticles to evaluate tumor targeting potential in …
Subtractive proteomics approach to Unravel the druggable proteins of the emerging pathogen Waddlia chondrophila and drug repositioning on its MurB protein
Waddlia chondrophila is an emerging pathogen that has been implicated in numerous
unpropitious pregnancy events in humans and ruminants. Taking into account its …
unpropitious pregnancy events in humans and ruminants. Taking into account its …
SiRNA Molecules as Potential RNAi Therapeutics to Silence RdRP Region and N-Gene of SARS-CoV-2: An In Silico Approach
M Hasan, AT Tasnim, AI Ashik, MB Chowdhury… - bioRxiv, 2022 - biorxiv.org
COVID-19 pandemic keeps pressing onward and effective treatment option against it is still
far-off. Since the onslaught in 2020, 13 different variants of SARS-CoV-2 have been …
far-off. Since the onslaught in 2020, 13 different variants of SARS-CoV-2 have been …
[HTML][HTML] Computational design of potential siRNA molecules for silencing of protease (3LC-like proteinase) and RNA-dependent RNA polymerase gene of SARS-CoV …
Since the origin of the SARS-CoV2 from Wuhan, in China, it has become a global threat to
public health and a WHO-declared world epidemic within 2 month of identification of the first …
public health and a WHO-declared world epidemic within 2 month of identification of the first …