[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

Leishmania vaccines: progress and problems

L Kedzierski, Y Zhu, E Handman - Parasitology, 2006 - cambridge.org
Leishmania are protozoan parasites spread by a sandfly insect vector and causing a
spectrum of diseases collectively known as leishmaniasis. The disease is a significant …

Leishmania species: A narrative review on surface proteins with structural aspects involved in host–pathogen interaction

RS Kaushal, N Naik, M Prajapati… - Chemical Biology & …, 2023 - Wiley Online Library
In tropical and subtropical regions of the world, leishmaniasis is endemic and causes a
range of clinical symptoms in people, from severe tegumentary forms (such as cutaneous …

[HTML][HTML] Development of Leishmania vaccines: predicting the future from past and present experience

JM Mutiso, JC Macharia, MN Kiio… - Journal of biomedical …, 2013 - ncbi.nlm.nih.gov
Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement
and fatal systemic infection. Resistance to infection is associated with a T-helper-1 immune …

Persistent parasites and immunologic memory in cutaneous leishmaniasis: implications for vaccine designs and vaccination strategies

I Okwor, J Uzonna - Immunologic research, 2008 - Springer
Despite a plethora of publications on the murine model of cutaneous leishmaniasis and their
contribution to our understanding of the factors that regulate the development of CD4+ T cell …

Insights into Leishmania Molecules and Their Potential Contribution to the Virulence of the Parasite

EK Elmahallawy, AAM Alkhaldi - Veterinary Sciences, 2021 - mdpi.com
Neglected parasitic diseases affect millions of people worldwide, resulting in high morbidity
and mortality. Among other parasitic diseases, leishmaniasis remains an important public …

Identifying vaccine targets for anti-leishmanial vaccine development

S Sundar, B Singh - Expert review of vaccines, 2014 - Taylor & Francis
Leishmaniasis is a neglected tropical disease spread by an arthropod vector. It remains a
significant health problem with an incidence of 0.2–0.4 million visceral leishmaniasis and …

A Reverse Vaccinology Approach for the Identification of Potential Vaccine Candidates from Leishmania spp

L John, GJ John, T Kholia - Applied biochemistry and biotechnology, 2012 - Springer
Leishmaniasis is a group of diseases with a spectrum of clinical manifestations ranging from
cutaneous ulcers to visceral leishmaniasis, which results from the bite of an infected sandfly …

Induction of protection against leishmaniasis in susceptible BALB/c mice using simple DOTAP cationic nanoliposomes containing soluble Leishmania antigen (SLA)

H Firouzmand, A Badiee, A Khamesipour, VH Shargh… - Acta tropica, 2013 - Elsevier
A suitable adjuvant and delivery system are needed to develop an effective vaccine against
leishmaniasis. To induce a Th1 type of response and protection in BALB/c mice against …

[HTML][HTML] Molecular identification of parasites causing cutaneous leishmaniasis in Panama

AC Miranda, KA González, F Samudio… - The American Journal …, 2021 - ncbi.nlm.nih.gov
Isolates from 475 cutaneous leishmaniasis (CL) patients from three endemic regions were
studied by three typing techniques. The molecular analysis from lesion scrapings based on …