STK19 is a transcription-coupled repair factor that participates in UVSSA ubiquitination and TFIIH loading
Y Tan, M Gao, Y Huang, D Zhan, S Wu… - Nucleic Acids …, 2024 - academic.oup.com
Transcription-coupled repair (TCR) is the major pathway to remove transcription-blocking
lesions. Although discovered for nearly 40 years, the mechanism and critical players of …
lesions. Although discovered for nearly 40 years, the mechanism and critical players of …
RNA polymerase tracking along damaged DNA: Impact on DNA repair and mutagenesis
DNA base lesions interfere with the fundamental processes of DNA replication and
transcription and therefore impact genome stability and cell viability if not efficiently repaired …
transcription and therefore impact genome stability and cell viability if not efficiently repaired …
Genome-wide analysis of transcription-coupled repair reveals novel transcription events in Caenorhabditis elegans
Bulky DNA adducts such as those induced by ultraviolet light are removed from the
genomes of multicellular organisms by nucleotide excision repair, which occurs through two …
genomes of multicellular organisms by nucleotide excision repair, which occurs through two …
Genetic background sets the trajectory of cancer evolution
Human cancers are heterogeneous. Their genomes evolve from genetically diverse
germlines in complex and dynamic environments, including exposure to potential …
germlines in complex and dynamic environments, including exposure to potential …
Selection efficacy differs between lifestages in the haploid-diploid Marchantia polymorpha subsp. ruderalis
Ploidy has profound effects on evolution. Perhaps the most compelling effect is related to
dominance: In cells with more than one genome copy, the effects of non-dominant …
dominance: In cells with more than one genome copy, the effects of non-dominant …