Acne vulgaris, probiotics and the gut-brain-skin axis-back to the future?

WP Bowe, AC Logan - Gut pathogens, 2011 - Springer
Over 70 years have passed since dermatologists John H. Stokes and Donald M. Pillsbury
first proposed a gastrointestinal mechanism for the overlap between depression, anxiety and …

Neurovascular unit dysfunction with blood-brain barrier hyperpermeability contributes to major depressive disorder: a review of clinical and experimental evidence

S Najjar, DM Pearlman, O Devinsky, A Najjar… - Journal of …, 2013 - Springer
About one-third of people with major depressive disorder (MDD) fail at least two
antidepressant drug trials at 1 year. Together with clinical and experimental evidence …

[HTML][HTML] Blood brain barrier and inflammation in depression

EM Medina-Rodriguez, E Beurel - Neurobiology of disease, 2022 - Elsevier
The blood brain barrier (BBB) is a vital structure to protect the brain, tightly filtering the
passage of nutrients and molecules from the blood to the brain. This is critical for …

Acne vulgaris, probiotics and the gut-brain-skin axis: from anecdote to translational medicine

W Bowe, NB Patel, AC Logan - Beneficial microbes, 2014 - wageningenacademic.com
Acne vulgaris has long been postulated to feature a gastrointestinal mechanism, dating back
80 years to dermatologists John H. Stokes and Donald M. Pillsbury. They hypothesised that …

Depression and anxiety in patients with hereditary angioedema

AS Fouche, EFH Saunders, T Craig - Annals of Allergy, Asthma & …, 2014 - Elsevier
Background Hereditary angioedema (HAE) is characterized by edematous swelling attacks
of the face, extremities, abdomen, genitalia, and upper airway. The potential for laryngeal …

Antidepressant‐like effect induced by systemic and intra‐hippocampal administration of DNA methylation inhibitors

AJ Sales, C Biojone, MS Terceti… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Epigenetic modifications are thought to play an important
role in the neurobiology of depression. Antidepressant treatment induces histone acetylation …

Kinin B1 receptors as a therapeutic target for inflammation

F Qadri, M Bader - Expert opinion on therapeutic targets, 2018 - Taylor & Francis
Introduction: Kinins are peptide mediators exerting their pro-inflammatory actions by the
selective stimulation of two distinct G-protein coupled receptors, termed BKB1R and BKB2R …

Ischemic stroke and traumatic brain injury: The role of the kallikrein–kinin system

C Albert-Weißenberger, AL Sirén… - Progress in neurobiology, 2013 - Elsevier
Acute ischemic stroke and traumatic brain injury are a major cause of mortality and
morbidity. Due to the paucity of therapies, there is a pressing clinical demand for new …

Synergistic effects of celecoxib and bupropion in a model of chronic inflammation-related depression in mice

IS Maciel, RBM Silva, FB Morrone, JB Calixto… - PLoS …, 2013 - journals.plos.org
This study was aimed to characterize the depression-like behaviour in the classical model of
chronic inflammation induced by Complete Freund's Adjuvant (CFA). Male Swiss mice …

Improvement of depressive behavior by Sweetme Sweet Pumpkin™ and its active compound, β-carotene

NR Kim, HY Kim, MH Kim, HM Kim, HJ Jeong - Life sciences, 2016 - Elsevier
Abstract Aims Sweetme Sweet Pumpkin™(SSP, baked Cucurbita moschata Duch.) has
been used to treat patients with depression in Korea. However, the role of SSP in improving …