Adverse outcome pathways (AOPs) organize knowledge on the progression of toxicity
through levels of biological organization. By determining the linkages between toxicity …

Background The high production volume of engineered nanomaterials (ENMs) may lead to
high pressure on the environment, and a scientific assessment of ENMs that bioaccumulate …

Interspecies sensitivity to the same chemical can be several orders of magnitude different.
Quantifying toxicologically internal levels and toxicokinetic (TK) parameters is critical in …

The exposure of ecologically critical invertebrate species to biologically active
pharmaceuticals poses a serious risk to the aquatic ecosystem. Yet, the fate and toxic effects …

Species sensitivity to neonicotinoids has been shown to be highly variable among aquatic
invertebrates. Toxicokinetic and toxicodynamic (TKTD) models were constructed to …

Extensive application of antibiotics leads to their ubiquitous occurrence in coastal aquatic
environments. However, it remains largely unknown whether antibiotics can be …

Internal concentrations link external exposure to the potential effect, as they reflect what the
organisms actually take up and experience physiologically. In this study, we investigated …

Natural wetlands have been recognized as a natural reactor for degradation and elimination
of environmental pollutants. The Upo Wetland, the largest inland wetland in Korea, is mainly …

The potential bioaccumulation and distribution of antibiotics in non-target organisms have
been inadequately studied in spite of their widespread occurrence in aquatic systems. We …

Biotransformation is a key process that can greatly influence the bioaccumulation potential
and toxicity of organic compounds. In this study, biotransformation of seven frequently used …