Object detection as a subfield within computer vision has achieved remarkable progress,
which aims to accurately identify and locate a specific object from images or videos. Such …

In 2012, it was discovered that precise gene editing could be induced in target DNA using
the reprogrammable characteristics of the CRISPR system. Since then, several studies have …

Cas12a, a CRISPR-associated protein complex, has an inherent ability to cleave DNA
substrates and is utilized in diagnostic tools to identify DNA molecules. We demonstrate that …

CRISPR-Cas12a is an accurate and responsive biosensing technique, but its limited stability
has restricted its widespread applications. To address this, we propose a strategy using …

CRISPR/Cas systems offer a powerful sensing mechanism to transduce sequence‐specific
information into amplified analytical signals. However, performing multiplexed CRISPR/Cas …

Background. The goal of this study was to see whether Helicobacter pylori (H. pylori) in the
oral cavity might adversely affect the outcome of eradication therapy for gastric H. pylori …

Rapid and ultrasensitive point-of-care RNA detection plays a critical role in the diagnosis
and management of various infectious diseases. The gold-standard detection method of …

There is a broad diversity among Cas12a endonucleases that possess nucleic acid
detection and gene-editing capabilities, but few are studied extensively. Here, we present an …

CRISPR-Cas-based diagnostics have the potential to elevate nucleic acid detection.
CRISPR-Cas systems can be combined with a pre-amplification step in a one-pot reaction to …

We report the development and initial validation of a paper-based nucleic acid testing
platform that integrates Loop-mediated isothermal amplification (LAMP) with clustered …