Anthelmintics in the future: current trends in the discovery and development of new drugs against gastrointestinal nematodes

M Zajíčková, LT Nguyen, L Skálová, LR Stuchlíková… - Drug Discovery …, 2020 - Elsevier
Highlights•Gastrointestinal nematodes are resistant to available anthelmintics.•No new
anthelmintic on the market for several years.•A target-based approach, drug repurposing or …

A Systematic Review on Comparative Analysis, Toxicology, and Pharmacology of Medicinal Plants Against Haemonchus contortus

R Ali, M Rooman, S Mussarat, S Norin, S Ali… - Frontiers in …, 2021 - frontiersin.org
Background: Haemonchus contortus is an important pathogenic nematode parasite and
major economic constraint of small ruminants in tropics and subtropics regions. This review …

Assessment of anthelmintic activity and bio-guided chemical analysis of Persea americana seed extracts

A Soldera-Silva, M Seyfried, LH Campestrini… - Veterinary …, 2018 - Elsevier
The aim of this study was to characterize the extracts and fractions of Persea americana
Mill.(Avocado) seeds and to determine the composition and the in vitro anthelmintic activity …

In vitro anthelmintic activity of the crude hydroalcoholic extract of Piper cubeba fruits and isolated natural products against gastrointestinal nematodes in sheep

MS de Paula Carlis, A Feboli, AC de Laurentiz… - Veterinary …, 2019 - Elsevier
This study describes the in vitro anthelmintic activity of a hydroalcoholic extract from the fruit
of Piper cubeba and its major isolated components against the eggs and larvae of …

[HTML][HTML] In vitro anthelmintic activity of grape pomace extract against gastrointestinal nematodes of naturally infected sheep

SCS Soares, GC de Lima, AC Laurentiz… - International journal of …, 2018 - Elsevier
Grape pomace obtained as a byproduct of industrial processing of grapes retains nutrients
and substances with anthelmintic potential such as saponins, tannins, and flavonoids …

Discovery of potential ovicidal natural products using metabolomics

DGL Borges, JT Echeverria, TL de Oliveira… - PLoS …, 2019 - journals.plos.org
Plant extracts are a potential source of new compounds for nematode control and may be an
excellent alternative for the control gastrointestinal nematodes that are resistant to …

[HTML][HTML] Liver status of goats fed with cactus cladodes genotypes resistant to Dactylopius opuntiae

TGP da Silva, JA Munhame, LA Lopes… - Small Ruminant …, 2021 - Elsevier
The effects of diets containing cactus cladodes genotypes resistant to Dactylopius opuntiae
on the hepatic condition of crossbred male goats were evaluated. Thirty-six goats (19.0±2.8 …

Kidney changes in lambs fed cactus pear varieties resistant to Dactylopius opuntiae as the only roughage

UA Usman, ACA de Moraes, TGP da Silva… - Tropical Animal Health …, 2022 - Springer
This study aimed to evaluate the effects of four varieties of cactus pear resistant to carmine
cochineal as exclusive roughage for lambs on the biochemical, histopathological, and …

Opuntia ficus-indica cladode extract is an embryotoxic, larvicidal, and oviposition-deterrent agent for the diamondback moth, Plutella xylostella

ECB Ferrreira, ICV Nova, WA de Almeida… - Crop Protection, 2021 - Elsevier
The search for new compounds to control Plutella xylostella, the main pest of Brassica crops,
has been stimulated by the environmental impact of the insecticides currently used and …

Anthelmintic activity of fruit extract and fractions of Piper longum L. In vitro

KG Koorse, S Samraj, P John, PM Narayanan… - Pharmacognosy …, 2018 - phcogj.com
The present study was aimed to assess the in vitro ovicidal, larvicidal and adulticidal activity
of methanolic extract and its fractions from fruits of Piper longum against strongyle ova …