The use of biomarkers in biomonitoring: a 2-tier approach assessing the level of pollutant-induced stress syndrome in sentinel organisms

A Viarengo, D Lowe, C Bolognesi, E Fabbri… - … and Physiology Part C …, 2007 - Elsevier
The paper outlines a 2-tier approach for wide-scale biomonitoring programmes. To obtain a
high level of standardization, we suggest the use of caged organisms (mussels or fish). An …

Multixenobiotic resistance as a cellular defense mechanism in aquatic organisms

SM Bard - Aquatic Toxicology, 2000 - Elsevier
Multixenobiotic resistance in aquatic organisms exposed to natural toxins or anthropogenic
contaminants is a phenomenon analogous to multidrug resistance in mammalian tumor cell …

[图书][B] The toxicology of fishes

RT Di Giulio, DE Hinton - 2008 - taylorfrancis.com
When looking for a book on fish toxicology, you might find one that discusses the
biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You …

Nitromusk and polycyclic musk compounds as long-term inhibitors of cellular xenobiotic defense systems mediated by multidrug transporters

T Luckenbach, D Epel - Environmental health perspectives, 2005 - ehp.niehs.nih.gov
Synthetic musk compounds, widely used as fragrances in consumer products, have been
detected in human tissue and, surprisingly, in aquatic organisms such as fish and mollusks …

Development of biomarkers to detect the effects of organic pollution on aquatic invertebrates: recent molecular, genotoxic, cellular and immunological studies on the …

DR Livingstone, JK Chipman… - International …, 2000 - inderscienceonline.com
Organic contaminants are continually entering aquatic environments and thence the tissues
of resident biota. Mussels and other molluscs are used worldwide as sentinels in pollution …

Stress proteins as molecular biomarkers for environmental toxicology

JA Ryan, LE Hightower - Stress-inducible cellular responses, 1996 - Springer
Biomarkers are increasingly being used in environmental monitoring to provide evidence
that organisms have been exposed to, or affected by, xenobiotic chemicals. Usually, these …

Induction of a multixenobiotic resistance protein (MXR) in the Asiatic clam Corbicula fluminea after heavy metals exposure

M Achard, M Baudrimont, A Boudou, JP Bourdineaud - Aquatic toxicology, 2004 - Elsevier
Multixenobiotic resistance mechanisms (MXR) related to the mammalian P-glycoprotein
multidrug transporter protein (P-gp) are known to occur in several marine invertebrates. In …

[HTML][HTML] Use of multidrug transporters as first lines of defense against toxins in aquatic organisms

D Epel - Comparative Biochemistry and Physiology Part A …, 1998 - Elsevier
Multidrug transporters are ATP-dependent transport proteins which efflux a variety of
moderately hydrophobic compounds out of cells. This article reviews the biology and …

ABCB-and ABCC-type transporters confer multixenobiotic resistance and form an environment-tissue barrier in bivalve gills

T Luckenbach, D Epel - American Journal of Physiology …, 2008 - journals.physiology.org
Aquatic organisms and, in particular, filter feeders, such as mussels, are continuously
exposed to toxicants dissolved in the water and, presumably, require adaptations to avoid …

A pollution‐monitoring pilot study involving contaminant and biomarker measurements in the Seine Estuary, France, using zebra mussels (Dreissena polymorpha)

C Minier, A Abarnou… - … and Chemistry: An …, 2006 - Wiley Online Library
Zebra mussel (Dreissena polymorpha) is an invasive species that has proliferated in
European and North American rivers and lakes during the last century. In this study, D …