Executive summary Essential medicines satisfy the priority health-care needs of the
population. Essential medicines policies are crucial to promoting health and achieving …

In global health, critical challenges have arisen from infectious diseases, including the
emergence and reemergence of old and new infectious diseases. Emergence and …

A critical review of the development of specific chemotherapeutic approaches for the
management of American Trypanosomiasis or Chagas disease is presented, including …

The production of counterfeit or substandard anti-infective drugs is a widespread and under-
recognised problem that contributes to morbidity, mortality, and drug resistance, and leads to …

Background Recruitment of participants into randomised controlled trials (RCTs) is critical for
successful trial conduct. Although there have been two previous systematic reviews on …

New formulations, therapeutic switching of the established drugs amphotericin B and
paromomycin, and the serendipitous discovery of miltefosine have markedly improved …

Sound regulatory systems are critical for protecting public health against use of medical
products which do not meet international standards of quality, safety and efficacy. This …

Leishmaniasis is a vector-borne parasitic disease caused by Leishmania species. The
disease affects humans and animals, particularly dogs, provoking cutaneous …

Mathias Risse discusses whether the global system of territorial sovereignty that emerged in
the fifteenth century can be said to harm the poorer societies. This question is distinct from …

In this article, we discuss the challenges, recent developments and new thinking on drug
R&D for neglected diseases through public–private partnerships. The focus on virtual drug …