Tumor cells manipulate the local environment in which they grow, creating a tumor
microenvironment (TME) that promotes tumor survival and metastasis. The TME is an …

Oncolytic viruses (OVs) are emerging as potential treatment options for cancer. Natural and
genetically engineered viruses exhibit various antitumor mechanisms. OVs act by direct …

Cytokines have proven to be effective for cancer therapy, however whilst low-dose
monotherapy with cytokines provides limited therapeutic benefit, high-dose treatment can …

Glioblastoma (GBM) is the most common primary malignant tumor in the brain, accounting
for 51.4% of all primary brain tumors. GBM has a highly immunosuppressive tumor …

Oncolytic virotherapy has become an important strategy in cancer immunotherapy. Oncolytic
virus (OV) can reshape the tumor microenvironment (TME) through its replication-mediated …

Background Triple-negative breast cancer (TNBC) corresponds to approximately 20% of all
breast tumors, with a high propensity for metastasis and a poor prognosis. Because TNBC …

Immunotherapies using immune checkpoint inhibitors (ICIs) and chimeric antigen receptor
(CAR) T-cell therapy have achieved successful results against several types of human …

Surgical removal of tumors remains a front-line therapy for many types of cancer. However,
this treatment often fails to eradicate disease due to either recurrence of the original tumor or …

Lung cancer is one of the malignant tumors that seriously threaten human health worldwide,
while the covid-19 virus has become people's nightmare after the coronavirus pandemic …

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the
accumulation of lipid peroxides. In this study, we explore the combination of a ferroptosis …