3-Spiro [cyclopropa [a] pyrrolizine]-and 3-spiro [3-azabicyclo [3.1. 0] hexane] oxindoles were
prepared in moderate to high yields via one-pot three-component reactions using …

The FDA Green Book is a list of all drug products that have been approved by the FDA for
use in veterinary medicine. The Green Book, as published, lacks structural information …

N-fused pyrrolidinyl spirooxindole belongs to a class of privileged heterocyclic scaffolds and
is prevalent in natural alkaloids and synthetic pharmaceutical molecules. To realize the …

In this study, four novel Pt (II) and Ni (II) complexes of octahydropyrrolo [3, 4-c] pyrrole,
consisting of pyrrolidine fused to pyrrolidine-2, 5-dione, N-benzoylthiourea derivatives were …

A modest library of a set of dispirooxindole-pyrrolothiazole derivatives 5a–n has been
synthesized through multicomponent technique employing 1, 3-dipolar cycloaddition …

The synthesis of various fused spiropyrrolidine oxindoles from isatins, amino acids, and
heterobicyclic alkenes through a 1, 3‐dipolar cycloaddition is described. For the first time …

Four phthalazinones (CIDs 22334057, 22333974, 22334032, 22334012) and one
isoquinolone (CID 5224943) were previously shown to be potent enhancers of antifungal …

A new series of highly-functionalized spiro compounds of pyrrole were synthesized by a one
pot, step-economic condensation of isatin, arylamine and β-keto ester catalyzed by wet …

The spiro-oxindole derivatives were synthesized via a 1, 3-dipolar cycloaddition approach
and characterized by FT-IR, 1H, 13C NMR and mass spectral techniques. The single crystal …

ABSTRACT A facile regio and stereoselective synthesis of novel spiro [indolin-3, 2′-
pyrrolidin]-2-one's have been accomplished through 1, 3-dipolar cycloaddition of …