Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human
body including bearing loads in articular joints and intervertebral discs, providing joint …

Post-traumatic osteoarthritis (PTOA) develops after joint injury. Specifically, patients with
anterior cruciate ligament (ACL) injury have a high risk of developing PTOA. In this review …

Osteoarthritis (OA) is a progressive chronic inflammation that leads to cartilage
degeneration. OA Patients are commonly given pharmacological treatment, but the available …

Cartilage-targeting delivery of therapeutic agents is still an effective strategy for osteoarthritis
(OA) therapy. Recently, scavenging for reactive oxygen species (ROS) and activating …

Negatively charged tissues are ubiquitous in the human body and are associated with a
number of common diseases yet remain an outstanding challenge for targeted drug delivery …

Articular cartilage is a remarkable tissue whose sophisticated composition and architecture
allow it to withstand complex stresses within the joint. Once injured, cartilage lacks the …

Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …

Recent years have witnessed significant increase in both fundamental and clinical studies
evaluating DDS for osteoarthritis. Steroid encapsulating polymeric microparticles for longer …

Osteoarthritis (OA) is a progressive and degenerative disease, which is no longer confined
to the elderly. So far, current treatments are limited to symptom relief, and no valid OA …

Background Most in vitro studies of potential osteoarthritis (OA) therapies have used
cartilage monocultures, even though synovium is a key player in mediating joint …