Diffuse large B-cell lymphoma variants: an update

N Sukswai, K Lyapichev, JD Khoury, LJ Medeiros - Pathology, 2020 - Elsevier
Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma, representing
approximately one-third of all cases worldwide. In the World Health Organization (WHO) …

Extranodal diffuse large B cell lymphoma: molecular features, prognosis, and risk of central nervous system recurrence

TA Ollila, AJ Olszewski - Current treatment options in oncology, 2018 - Springer
Opinion statement Diffuse large B cell lymphoma (DLBCL) arises from extranodal organs in
about 30% of cases. Its prognosis and risk of recurrence in the central nervous system …

PD-1 blockade with nivolumab in relapsed/refractory primary central nervous system and testicular lymphoma

L Nayak, FM Iwamoto, A LaCasce… - Blood, The Journal …, 2017 - ashpublications.org
Primary central nervous system (CNS) lymphoma (PCNSL) and primary testicular lymphoma
(PTL) are rare extranodal large B-cell lymphomas with similar genetic signatures. There are …

Targetable genetic features of primary testicular and primary central nervous system lymphomas

B Chapuy, MGM Roemer, C Stewart… - Blood, The Journal …, 2016 - ashpublications.org
Primary central nervous system lymphomas (PCNSLs) and primary testicular lymphomas
(PTLs) are extranodal large B-cell lymphomas (LBCLs) with inferior responses to current …

Diffuse large B‐cell lymphoma with testicular involvement: outcome and risk of CNS relapse in the rituximab era

R Kridel, D Telio, D Villa, LH Sehn… - British journal of …, 2017 - Wiley Online Library
The addition of rituximab has improved outcomes in diffuse large B‐cell lymphoma (DLBCL),
however, there remains limited information on the impact of rituximab in those with testicular …

[HTML][HTML] PD-L1+ tumor-associated macrophages and PD-1+ tumor-infiltrating lymphocytes predict survival in primary testicular lymphoma

M Pollari, O Brück, T Pellinen, P Vähämurto… - …, 2018 - ncbi.nlm.nih.gov
Primary testicular lymphoma is a rare and aggressive lymphoid malignancy, most often
representing diffuse large B-cell lymphoma histologically. Tumor-associated macrophages …

IELSG30 phase 2 trial: intravenous and intrathecal CNS prophylaxis in primary testicular diffuse large B-cell lymphoma

A Conconi, A Chiappella, AJM Ferreri… - Blood …, 2024 - ashpublications.org
Primary testicular diffuse large B-cell lymphoma (PTL) is characterized by high risk of
contralateral testis and central nervous system (CNS) relapse. Chemoimmunotherapy with …

Distribution and clinical impact of molecular subtypes with dark zone signature of DLBCL in a Japanese real-world study

T Urata, Y Naoi, A Jiang, M Boyle, K Sunami… - Blood …, 2023 - ashpublications.org
The distribution and clinical impact of cell-of-origin (COO) subtypes of diffuse large B-cell
lymphoma (DLBCL) outside Western countries remain unknown. Recent literature also …

Signaling pathway and dysregulation of PD1 and its ligands in lymphoid malignancies

Y Xia, LJ Medeiros, KH Young - … et Biophysica Acta (BBA)-Reviews on …, 2016 - Elsevier
Tumor cells evade immune destruction, at least partially, by upregulating inhibitory signals to
limit effector T cell activation. Programmed death 1 (PD-1) is one of the most critical co …

T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma

SK Leivonen, M Pollari, O Brück, T Pellinen… - …, 2018 - pmc.ncbi.nlm.nih.gov
Primary testicular lymphoma is a rare lymphoid malignancy, most often, histologically,
representing diffuse large B-cell lymphoma. The tumor microenvironment and limited …