[HTML][HTML] Insights into a crucial role of TRIP13 in human cancer

S Lu, J Qian, M Guo, C Gu, Y Yang - Computational and structural …, 2019 - Elsevier
Abstract Thyroid Hormone Receptor Interacting Protein 13 (TRIP13) plays a key role in
regulating mitotic processes, including spindle assembly checkpoint and DNA repair …

A gene signature of survival prediction for kidney renal cell carcinoma by multi-omic data analysis

F Hu, W Zeng, X Liu - International journal of molecular sciences, 2019 - mdpi.com
Kidney renal cell carcinoma (KIRC), which is the most common subtype of kidney cancer,
has a poor prognosis and a high mortality rate. In this study, a multi-omics analysis is …

[HTML][HTML] Klotho restoration via ACE2 activation: A potential therapeutic strategy against acute kidney injury-diabetes comorbidity

A Kale, V Shelke, H Sankrityayan, N Dagar… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Acute kidney injury (AKI) is a collection of clinical syndromes with persistent increases in
morbidity and mortality rates. Hyperglycemia is a risk factor for AKI development. Renin …

TRIP13− a potential drug target in cancer pharmacotherapy

SJ Bunu, H Cai, L Wu, H Zhang, Z Zhou, Z Xu, J Shi… - Bioorganic …, 2024 - Elsevier
Abstract ATPases Associated with Diverse Cellular Activity (AAA+ ATPases) are important
enzymatic functional proteins in human cells. Thyroid Hormone Receptor Interacting Protein …

Selective cannabinoid 2 receptor stimulation reduces tubular epithelial cell damage after renal ischemia-reperfusion injury

JD Pressly, SM Mustafa, AH Abidi, S Alghamdi… - … of Pharmacology and …, 2018 - ASPET
Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI), which is an
increasing problem in the clinic and has been associated with elevated rates of mortality …

Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin

K Mittal, GW Cooper, BP Lee, Y Su, KT Skinner… - Communications …, 2024 - nature.com
Wilms tumor (WT) is the most common renal malignancy of childhood. Despite
improvements in the overall survival, relapse occurs in~ 15% of patients with favorable …

Erythropoietin derived peptide improved endoplasmic reticulum stress and ischemia-reperfusion related cellular and renal injury

Y Zhang, Q Wang, A Liu, Y Wu, F Liu, H Wang… - Frontiers in …, 2020 - frontiersin.org
Ischemia-reperfusion (IR) injury often affects transplant and native kidneys alike. IR injury is
one of the main causes of acute kidney injury (AKI) and further associated with the …

[HTML][HTML] Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury

JB Hu, GL Song, D Liu, SJ Li, JH Wu, XQ Kang, J Qi… - Drug …, 2017 - ncbi.nlm.nih.gov
In an attempt to improve therapeutic efficacy of dexamethasone (DXM)-loaded solid lipid
nanoparticles (NPs) for renal ischemia-reperfusion injury (IRI)-induced acute renal injury …

[HTML][HTML] Activation of the cannabinoid receptor 2 increases renal perfusion

JD Pressly, H Soni, S Jiang, J Wei… - Physiological …, 2019 - journals.physiology.org
Acute kidney injury (AKI) is an increasing clinical problem that is associated with chronic
kidney disease progression. Cannabinoid receptor 2 (CB2) activation has been shown to …

[HTML][HTML] DNA damage is overcome by TRIP13 overexpression during cisplatin nephrotoxicity

T Hama, PKB Nagesh, P Chowdhury, BM Moore… - JCI insight, 2021 - ncbi.nlm.nih.gov
Cisplatin is a commonly used chemotherapeutic agent to treat a wide array of cancers that is
frequently associated with toxic injury to the kidney due to oxidative DNA damage and …