Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

In conventional positron emission tomography (PET), only one radiotracer can be imaged at
a time, because all PET isotopes produce the same two 511 keV annihilation photons. Here …

Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Immunotherapy, specifically the introduction of immune checkpoint inhibitors, has
transformed the treatment of cancer, enabling long-term tumour control even in individuals …

Immunotherapy is becoming the mainstay for treatment of a variety of malignancies, but only
a subset of patients responds to treatment. Tumor-infiltrating CD8-positive (CD8+) T …

Senescence refers to a cellular state featuring a stable cell‐cycle arrest triggered in
response to stress. This response also involves other distinct morphological and intracellular …

The rapidly advancing field of cancer immunotherapy is currently limited by the scarcity of
noninvasive and quantitative technologies capable of monitoring the presence and …

Antibodies have clearly demonstrated their utility as therapeutics, providing highly selective
and effective drugs to treat diseases in oncology, hematology, cardiology, immunology and …