Ketogenic diet and weight loss: is there an effect on energy expenditure?

A Basolo, S Magno, F Santini, G Ceccarini - Nutrients, 2022 - mdpi.com
A dysregulation between energy intake (EI) and energy expenditure (EE), the two
components of the energy balance equation, is one of the mechanisms responsible for the …

Energy balance and control of body weight: Possible effects of meal timing and circadian rhythm dysregulation

A Basolo, S Bechi Genzano, P Piaggi, J Krakoff… - Nutrients, 2021 - mdpi.com
Conservation of the energy equilibrium can be considered a dynamic process and variations
of one component (energy intake or energy expenditure) cause biological and/or behavioral …

Resting energy expenditure: from cellular to whole‐body level, a mechanistic historical perspective

SB Heymsfield, B Smith, J Dahle, S Kennedy… - …, 2021 - Wiley Online Library
The basis of heat generated by the human body has been a source of speculation and
research for more than 2,000 years. Basal heat production, now usually referred to as …

[HTML][HTML] Hepatic FGF21: its emerging role in inter-organ crosstalk and cancers

SUI Yue, C Jianping - International Journal of Biological Sciences, 2022 - ncbi.nlm.nih.gov
Fibroblast growth factor (FGF) 21 is one of the FGF members with special endocrine
properties. In the last twenty years, it has attracted intense research and development for its …

[HTML][HTML] Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and-independent mechanisms

J Sostre-Colón, K Uehara, AEG Whitlock, MJ Gavin… - Cell reports, 2021 - cell.com
Organismal stressors such as cold exposure require a systemic response to maintain body
temperature. Brown adipose tissue (BAT) is a key thermogenic tissue in mammals that …

Beneficial effects of whole-body cryotherapy on glucose homeostasis and amino acid profile are associated with a reduced myostatin serum concentration

M Kozłowska, J Kortas, M Żychowska, J Antosiewicz… - Scientific Reports, 2021 - nature.com
The study investigated the effect of single and chronic (10 sessions) whole-body cryotherapy
(WBC; 3-min,− 110° C) on amino acid (AA) profile, myostatin, fibroblast growth factor 21 …

HCV-induced autophagy and innate immunity

J Lee, JHJ Ou - Frontiers in Immunology, 2024 - frontiersin.org
The interplay between autophagy and host innate immunity has been of great interest.
Hepatitis C virus (HCV) impedes signaling pathways initiated by pattern-recognition …

Reduced brown adipose tissue activity during cold exposure is a metabolic feature of the human thrifty phenotype

T Hollstein, K Vinales, KY Chen, AM Cypess, A Basolo… - Metabolism, 2021 - Elsevier
Background We recently demonstrated that thrifty subjects, characterized by a greater
decrease in 24 h energy expenditure (24hEE) during short-term fasting, have less capacity …

Critical role of FGF21 in diabetic kidney disease: from energy metabolism to innate immunity

Y Liang, Q Chen, Y Chang, J Han, J Yan… - Frontiers in …, 2024 - frontiersin.org
Diabetic kidney disease (DKD) stands as the predominant cause of chronic kidney disease
(CKD) on a global scale, with its incidence witnessing a consistent annual rise, thereby …

Impaired metabolic flexibility to fasting is associated with increased ad libitum energy intake in healthy adults

Y Unlu, P Piaggi, EJ Stinson, T Cabeza De Baca… - …, 2024 - Wiley Online Library
Objective We investigated how changes in 24‐h respiratory exchange ratio (RER) and
substrate oxidation during fasting versus an energy balance condition influence subsequent …