Apoptosis deficiency is one of the most important features observed in neoplastic diseases.
The Bcl-2 family is composed of a subset of proteins that act as decisive apoptosis …

The epithelial-mesenchymal transition (EMT) is a cellular process though which an epithelial
phenotypecan be converted into a phenotype of mesenchymal cells. Under physiological …

Hepatocellular carcinoma (HCC) is one of the most severe diseases worldwide. For the
different stages of HCC, there are different clinical treatment strategies, such as surgical …

Colon cancer (CC) is the third most common cancer worldwide. Emodin is an anthraquinone-
active substance that has the ability to affect tumor progression. Our study aims to explore …

Background: Chemoresistance is a main obstacle to effective esophageal cancer (EC)
therapy. We hypothesize that altered expression of microRNAs (miRNAs) play a role in EC …

Although fungi produce highly structurally diverse metabolites, many of which have served
as excellent sources of pharmaceuticals, no fungi‐derived agent has been approved as a …

Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide and its
incidence is steadily rising. Currently, sorafenib remains the only approved standard …

Many fungal metabolites show promising anticancer properties both in vitro and in animal
models, and some synthetic analogs of those metabolites have progressed into clinical …

Guttation is a common phenomenon in the fungal kingdom. Its occurrence and intensity
depend largely on culture conditions, such as growth medium composition or incubation …

As the third major reason of mortality related to cancer in the world, liver cancer is also the
fifth most frequent cancer. Unluckily, a majority of patients succumb and relapse though …