Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application

Z Song, Z Han, S Lv, C Chen, L Chen, L Yin… - Chemical Society …, 2017 - pubs.rsc.org
Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …

Synthesis of side-chain modified polypeptides

TJ Deming - Chemical reviews, 2016 - ACS Publications
Proteins have long fascinated scientists since their complex sequences and diversity of
chemical functionality can lead to structurally defined folded chains with highly specific …

Functional biodegradable polymers via ring-opening polymerization of monomers without protective groups

G Becker, FR Wurm - Chemical society reviews, 2018 - pubs.rsc.org
Biodegradable polymers are of current interest and chemical functionality in such materials
is often demanded in advanced biomedical applications. Functional groups often are not …

Secondary structures of synthetic polypeptide polymers

C Bonduelle - Polymer Chemistry, 2018 - pubs.rsc.org
Synthetic peptide-based polymers represent a unique class of macromolecules able to
mimic the properties of natural proteins in materials sciences since (1) they present the …

Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications

Z Song, H Fu, R Wang, LA Pacheco, X Wang… - Chemical Society …, 2018 - pubs.rsc.org
Synthetic polypeptides derived from the ring-opening polymerization of N-
carboxyanhydrides can spontaneously fold into stable secondary structures under specific …

Recent Advances and Future Perspectives of Synthetic Polypeptides from N-Carboxyanhydrides

Z Song, Z Tan, J Cheng - Macromolecules, 2019 - ACS Publications
Synthetic polypeptides, the analogues of natural proteins, are important biomaterials that
have found broad biomedical applications. Ring-opening polymerization of N …

A membrane-embedded macromolecular catalyst with substrate selectivity in live cells

Y Deng, T Wu, X Chen, Y Chen, Y Fei… - Journal of the …, 2022 - ACS Publications
Substrate selectivity is one of the most attractive features of natural enzymes from their “bind-
to-catalyze” working flow and is thus a goal for the development of synthetic enzyme mimics …

Helix-specific properties and applications in synthetic polypeptides

N Li, Y Lei, Z Song, L Yin - Current Opinion in Solid State and Materials …, 2023 - Elsevier
Polypeptides obtained from the ring-opening polymerization of N-carboxyanhydrides, as the
synthetic analogues of natural proteins, have drawn broad interests during the recent three …

Synthetic peptide branched polymers for antibacterial and biomedical applications

S Shabani, S Hadjigol, W Li, Z Si, D Pranantyo… - Nature Reviews …, 2024 - nature.com
Antimicrobial resistance is a major threat to human health, and this 'invisible pandemic'is a
looming public health crisis. Accordingly, both broad-spectrum and selective antimicrobial …

Biological applications of water-soluble polypeptides with ordered secondary structures

C Ge, H Ye, F Wu, J Zhu, Z Song, Y Liu… - Journal of Materials …, 2020 - pubs.rsc.org
Water-soluble polypeptides are a class of synthetic polymers with peptide bond frameworks
imitating natural proteins and have broad prospects in biological applications. The …