Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine

GL Parrilha, RG dos Santos, H Beraldo - Coordination Chemistry Reviews, 2022 - Elsevier
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Radiopharmaceutical treatments for cancer therapy, radionuclides characteristics, applications, and challenges

S Salih, A Alkatheeri, W Alomaim, A Elliyanti - Molecules, 2022 - mdpi.com
Advances in the field of molecular biology have had an impact on biomedical applications,
which provide greater hope for both imaging and therapeutics. Work has been intensified on …

A critical review of novel antibiotic resistance prevention approaches with a focus on postbiotics

MA Ozma, SR Moaddab, H Hosseini… - Critical reviews in …, 2024 - Taylor & Francis
Antibiotic resistance is a significant public health issue, causing illnesses that were once
easily treatable with antibiotics to develop into dangerous infections, leading to substantial …

In vitro and in vivo evaluation of 211At-labeled fibroblast activation protein inhibitor for glioma treatment

H Ma, F Li, G Shen, L Pan, W Liu, R Liang, T Lan… - Bioorganic & Medicinal …, 2022 - Elsevier
Glioma is the most common primary intracranial tumor without effective treatment. Positron
emission tomography tracers labeled with 68 Ga targeting fibroblast activation protein (FAP) …

Clinical advances and perspectives in targeted radionuclide therapy

N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …

Radioimmunotherapy in oncology: overview of the last decade clinical trials

A Rondon, J Rouanet, F Degoul - Cancers, 2021 - mdpi.com
Simple Summary Monoclonal antibody-bearing radionuclides have been under clinical
investigation over the last two decades for their use in theranostic (diagnostic and …

Bifunctional chelators for radiorhenium: Past, present and future outlook

DR Melis, AR Burgoyne, M Ooms… - RSC Medicinal Chemistry, 2022 - pubs.rsc.org
Targeted radionuclide therapy (TRNT) is an ever-expanding field of nuclear medicine that
provides a personalised approach to cancer treatment while limiting toxicity to normal …

Carrier systems of radiopharmaceuticals and the application in cancer therapy

T Zhang, H Lei, X Chen, Z Dou, B Yu, W Su… - Cell Death …, 2024 - nature.com
Radiopharmaceuticals play a vital role in cancer therapy. The carrier of
radiopharmaceuticals can precisely locate and guide radionuclides to the target, where …

Radioimmunotherapy of non-Hodgkin B-cell lymphoma: an update

F Cicone, G Santo, C Bodet-Milin, GL Cascini… - Seminars in Nuclear …, 2023 - Elsevier
Systemic radioimmunotherapy (RIT) is arguably the most effective and least toxic anticancer
treatment for non-Hodgkin lymphoma (NHL). In treatment-naïve patients with indolent NHL …

Site-specific Conjugation of 6 DOTA Chelators to a CA19-9-targeting scFv-Fc Antibody for Imaging and Therapy

LA Chen, YH Yu, WT Tian, WC Lin… - Journal of Medicinal …, 2023 - ACS Publications
Antibodies conjugated with diagnostic/therapeutic radionuclides are attractive options for
inoperable cancers lacking accurate imaging methods and effective therapeutics, such as …